John B Schell
Overview
Explore the profile of John B Schell including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
206
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Recent Articles
1.
Malouli D, Taher H, Mansouri M, Iyer R, Reed J, Papen C, et al.
Sci Immunol
. 2024 Oct;
9(100):eadp5216.
PMID: 39392895
Rhesus cytomegalovirus (RhCMV) vectors elicit major histocompatibility complex (MHC)-E-restricted CD8 T cells that stringently control simian immunodeficiency virus (SIV) in rhesus macaques. These responses require deletion of eight RhCMV chemokine-like...
2.
Harbour J, Abdelbary M, Schell J, Fancher S, McLean J, Nappi T, et al.
Cell Rep
. 2023 Apr;
42(5):112407.
PMID: 37083328
Poxvirus infections of the skin are a recent emerging public health concern, yet the mechanisms that mediate protective immunity against these viral infections remain largely unknown. Here, we show that...
3.
Abdulhaqq S, Ventura A, Reed J, Bashirova A, Bateman K, McDonald E, et al.
J Immunol
. 2021 Nov;
207(12):2913-2921.
PMID: 34810222
CD8 T cells are key mediators of antiviral and antitumor immunity. The isolation and study of Ag-specific CD8 T cells, as well as mapping of their MHC restriction, has practical...
4.
Harbour J, Lyski Z, Schell J, Thomas A, Messer W, Slifka M, et al.
J Immunol
. 2021 May;
206(11):2596-2604.
PMID: 33972374
The COVID-19 pandemic is a global health emergency, and the development of a successful vaccine will ultimately be required to prevent the continued spread and seasonal recurrence of this disease...
5.
Abdulhaqq S, Wu H, Schell J, Hammond K, Reed J, Legasse A, et al.
J Virol
. 2019 Jul;
93(19).
PMID: 31315990
Major histocompatibility complex E (MHC-E) is a highly conserved nonclassical MHC-Ib molecule that tightly binds peptides derived from leader sequences of classical MHC-Ia molecules for presentation to natural killer cells....
6.
Colonna L, Peterson C, Schell J, Carlson J, Tkachev V, Brown M, et al.
Nat Commun
. 2018 Oct;
9(1):4438.
PMID: 30361514
Allogeneic transplantation (allo-HCT) has led to the cure of HIV in one individual, raising the question of whether transplantation can eradicate the HIV reservoir. To test this, we here present...
7.
Tkachev V, Furlan S, Watkins B, Hunt D, Zheng H, Panoskaltsis-Mortari A, et al.
Sci Transl Med
. 2017 Sep;
9(408).
PMID: 28931653
A critical question facing the field of transplantation is how to control effector T cell (T) activation while preserving regulatory T cell (T) function. Standard calcineurin inhibitor-based strategies can partially...
8.
Furlan S, Watkins B, Tkachev V, Cooley S, Panoskaltsis-Mortari A, Betz K, et al.
Blood
. 2016 Oct;
128(21):2568-2579.
PMID: 27758873
One of the central challenges of transplantation is the development of alloreactivity despite the use of multiagent immunoprophylaxis. Effective control of this immune suppression-resistant T-cell activation represents one of the...
9.
Schell J, Bahl K, Folta-Stogniew E, Rose N, Buonocore L, Marx P, et al.
Virology
. 2015 Jan;
476:405-412.
PMID: 25591175
We reported previously on a vaccine approach that conferred apparent sterilizing immunity to SIVsmE660. The vaccine regimen employed a prime-boost using vectors based on recombinant vesicular stomatitis virus (VSV) and...
10.
Rose N, Buonocore L, Schell J, Chattopadhyay A, Bahl K, Liu X, et al.
Proc Natl Acad Sci U S A
. 2014 Nov;
111(47):16866-71.
PMID: 25385608
Self-propagating, infectious, virus-like vesicles (VLVs) are generated when an alphavirus RNA replicon expresses the vesicular stomatitis virus glycoprotein (VSV G) as the only structural protein. The mechanism that generates these...