John A Walker 2nd
Overview
Explore the profile of John A Walker 2nd including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
5
Citations
356
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Moreno-Sanchez I, Hernandez-Huertas L, Nahon-Cano D, Gomez-Marin C, Martinez-Garcia P, Treichel A, et al.
bioRxiv
. 2024 Oct;
PMID: 39416004
CRISPR-Cas13 systems are widely used in basic and applied sciences. However, its application has recently generated controversy due to collateral activity in mammalian cells and mouse models. Moreover, its efficiency...
2.
Katti A, Vega-Perez A, Foronda M, Zimmerman J, Zafra M, Granowsky E, et al.
Nat Biotechnol
. 2023 Aug;
42(3):437-447.
PMID: 37563300
Although single-nucleotide variants (SNVs) make up the majority of cancer-associated genetic changes and have been comprehensively catalogued, little is known about their impact on tumor initiation and progression. To enable...
3.
Yarnall M, Ioannidi E, Schmitt-Ulms C, Krajeski R, Lim J, Villiger L, et al.
Nat Biotechnol
. 2022 Nov;
41(4):500-512.
PMID: 36424489
Programmable genome integration of large, diverse DNA cargo without DNA repair of exposed DNA double-strand breaks remains an unsolved challenge in genome editing. We present programmable addition via site-specific targeting...
4.
Rothgangl T, Dennis M, Lin P, Oka R, Witzigmann D, Villiger L, et al.
Nat Biotechnol
. 2021 May;
39(8):949-957.
PMID: 34012094
Most known pathogenic point mutations in humans are C•G to T•A substitutions, which can be directly repaired by adenine base editors (ABEs). In this study, we investigated the efficacy and...
5.
Gao P, Lyu Q, Ghanam A, Lazzarotto C, Newby G, Zhang W, et al.
Genome Biol
. 2021 Mar;
22(1):83.
PMID: 33722289
Background: Most single nucleotide variants (SNVs) occur in noncoding sequence where millions of transcription factor binding sites (TFBS) reside. Here, a comparative analysis of CRISPR-mediated homology-directed repair (HDR) versus the...