John-Stephen Taylor
Overview
Explore the profile of John-Stephen Taylor including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
43
Citations
724
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0
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Recent Articles
1.
Yang H, Scruggs S, Chai M, Mathai G, Taylor J, Gross M
J Am Soc Mass Spectrom
. 2024 Jul;
35(8):1768-1774.
PMID: 38952267
Irradiation of the major conformation of duplex DNA found in cells (B form) produces cyclobutane pyrimidine dimers (CPDs) from adjacent pyrimidines in a head-to-head orientation () with the C5 substituents...
2.
Gutierrez-Bayona N, Scruggs S, Yang H, Chai M, Gross M, Taylor J
Biochemistry
. 2023 Jul;
62(15):2269-2279.
PMID: 37459251
G-quadruplexes are thought to play an important role in gene regulation and telomere maintenance, but developing probes for their presence and location is challenging due to their transitory and highly...
3.
Taylor J
Photochem Photobiol
. 2022 Aug;
99(2):277-295.
PMID: 35980594
While the photochemistry of duplex DNA has been extensively studied, the photochemistry of nonduplex DNA structures is largely unexplored. Because the structure and stereochemistry of DNA photoproducts depend on the...
4.
Wang Y, Cacchillo E, Niedzwiedzki D, Taylor J
Photochem Photobiol
. 2021 Sep;
98(2):442-454.
PMID: 34558720
The formation of cyclobutane pyrimidine dimers (CPDs) by a "dark" pathway in melanocytes has been attributed to chemisensitization by dioxetanes produced from peroxynitrite oxidation of melanin or melanin precursors. These...
5.
Lu C, Gutierrez-Bayona N, Taylor J
Nucleic Acids Res
. 2021 Apr;
49(8):4266-4280.
PMID: 33849058
Cyclobutane pyrimidine dimers (CPDs) are the major products of DNA produced by direct absorption of UV light, and result in C to T mutations linked to human skin cancers. Most...
6.
Smith-Carpenter J, Taylor J
Photochem Photobiol
. 2018 Aug;
95(1):252-266.
PMID: 30084501
While is it well known that human telomeric DNA sequences can adopt G-quadruplex structures, some promoters sequences have also been found to form G-quadruplexes, and over 40% of promoters contain...
7.
Taylor J
DNA Repair (Amst)
. 2015 Oct;
36:59-67.
PMID: 26493358
How DNA damaged is formed, recognized, and repaired in chromatin is an area of intense study. To better understand the structure activity relationships of damaged chromatin, mono and dinucleosomes containing...
8.
Cannistraro V, Pondugula S, Song Q, Taylor J
J Biol Chem
. 2015 Sep;
290(44):26597-609.
PMID: 26354431
Sunlight-induced C to T mutation hot spots in skin cancers occur primarily at methylated CpG sites that coincide with sites of UV-induced cyclobutane pyrimidine dimer (CPD) formation. The C and...
9.
10.
Song Q, Cannistraro V, Taylor J
Nucleic Acids Res
. 2014 Nov;
42(21):13122-33.
PMID: 25389265
Sunlight-induced C to T mutation hotspots in skin cancers occur primarily at methylated CpG sites that coincide with sites of UV-induced cyclobutane pyrimidine dimer (CPD) formation. The C or 5-methyl-C...