Johanna Viiri
Overview
Explore the profile of Johanna Viiri including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
551
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0
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Recent Articles
1.
Tamminen T, Koskela A, Toropainen E, Gurubaran I, Winiarczyk M, Liukkonen M, et al.
Oxid Med Cell Longev
. 2021 Dec;
2021:8028427.
PMID: 34917233
Chronic oxidative stress eventually leads to protein aggregation in combination with impaired autophagy, which has been observed in age-related macular degeneration. We have previously shown an effective age-related macular degeneration...
2.
Blasiak J, Koskela A, Pawlowska E, Liukkonen M, Ruuth J, Toropainen E, et al.
Int J Mol Sci
. 2021 Feb;
22(4).
PMID: 33567500
Age-related macular degeneration (AMD) is the most prevalent form of irreversible blindness worldwide in the elderly population. In our previous studies, we found that deficiencies in the nuclear factor, erythroid...
3.
Gurubaran I, Viiri J, Koskela A, Hyttinen J, Paterno J, Kis G, et al.
Int J Mol Sci
. 2020 Mar;
21(6).
PMID: 32183173
Increased oxidative stress and mitochondrial damage are observed in protein aggregation diseases, such as age-related macular degeneration (AMD). We have recently reported elevated levels of oxidative stress markers, damaged mitochondria,...
4.
Felszeghy S, Viiri J, Paterno J, Hyttinen J, Koskela A, Chen M, et al.
Redox Biol
. 2018 Sep;
20:1-12.
PMID: 30253279
Age-related macular degeneration (AMD) is a multi-factorial disease that is the leading cause of irreversible and severe vision loss in the developed countries. It has been suggested that the pathogenesis...
5.
Hyttinen J, Viiri J, Kaarniranta K, Blasiak J
Cell Mol Life Sci
. 2018 May;
75(16):2991-3008.
PMID: 29777261
Age-related macular degeneration (AMD) is the predominant cause of visual loss in old people in the developed world, whose incidence is increasing. This disease is caused by the decrease in...
6.
Jauhonen H, Laihia J, Oksala O, Viiri J, Sironen R, Alajuuma P, et al.
Graefes Arch Clin Exp Ophthalmol
. 2017 Aug;
255(12):2357-2362.
PMID: 28840310
Purpose: Our purpose was to investigate the effect of locally administered cis-urocanic (cis-UCA) in two experimental models of allergic conjunctivitis. Methods: The compound 48/80 (C48/80)-induced ocular irritation model (IgE-independent) and...
7.
Juuti-Uusitalo K, Koskela A, Kivinen N, Viiri J, Hyttinen J, Reinisalo M, et al.
Int J Mol Sci
. 2017 May;
18(5).
PMID: 28534814
The impairment of autophagic and proteasomal cleansing together with changes in pigmentation has been documented in retinal pigment epithelial (RPE) cell degeneration. However, the function and co-operation of these mechanisms...
8.
Kaarniranta K, Szalai E, Smedowski A, Hegyi Z, Kivinen N, Viiri J, et al.
Histol Histopathol
. 2015 Jan;
30(8):921-30.
PMID: 25597745
Macular corneal dystrophy is a rare autosomal recessive eye disease affecting primarily the corneal stroma. Abnormal accumulation of proteoglycan aggregates has been observed intra- and extracellularly in the stromal layer....
9.
Hyttinen J, Amadio M, Viiri J, Pascale A, Salminen A, Kaarniranta K
Ageing Res Rev
. 2014 Jul;
18:16-28.
PMID: 25062811
Processing of misfolded proteins is important in order for the cell to maintain its normal functioning and homeostasis. Three systems control the quality of proteins: chaperone-mediated refolding, proteasomal degradation of...
10.
Viiri J, Amadio M, Marchesi N, Hyttinen J, Kivinen N, Sironen R, et al.
PLoS One
. 2013 Aug;
8(7):e69563.
PMID: 23922739
Age-related macular degeneration (AMD) is the most common reason of visual impairment in the elderly in the Western countries. The degeneration of retinal pigment epithelial cells (RPE) causes secondarily adverse...