Johan R C van der Maarel
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Explore the profile of Johan R C van der Maarel including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Wien F, Gragera M, Matsuo T, Moroy G, Bueno-Carrasco M, Arranz R, et al.
Nucleic Acids Res
. 2025 Mar;
53(5).
PMID: 40066879
All organisms depend on specific proteins to compact and organize their genomes. In eukaryotes, histones fulfil this role, while bacterial chromosomes are shaped by nucleoid-associated proteins (NAPs). Among its pleiotropic...
2.
Easo George J, Basak R, Yadav I, Tan C, van Kan J, Wien F, et al.
Lab Chip
. 2024 Oct;
24(22):5137-5144.
PMID: 39363842
Regulation of protein mobility is a fundamental aspect of cellular processes. In this study, we examined the impact of DNA methylation on the diffusion of nucleoid associated protein Hfq. This...
3.
van der Maarel J
J Appl Crystallogr
. 2024 Feb;
56(Pt 6):1714-1720.
PMID: 38314141
A general formalism is presented for the isotropically averaged single-chain scattering function (form factor) of single, double, triple and higher-order helices, as well as twisted fibres consisting of concentric layers...
4.
Kubiak K, Wien F, Yadav I, Jones N, Vronning Hoffmann S, Le Cam E, et al.
QRB Discov
. 2023 Aug;
3:e15.
PMID: 37529279
Interactions between proteins and single-stranded DNA (ssDNA) are crucial for many fundamental biological processes, including DNA replication and genetic recombination. Thus, understanding detailed mechanisms of these interactions is necessary to...
5.
Korolev N, Zinchenko A, Soman A, Chen Q, Wong S, Berezhnoy N, et al.
Sci Rep
. 2022 Sep;
12(1):15558.
PMID: 36114220
Large topologically associated domains (TADs) contain irregularly spaced nucleosome clutches, and interactions between such clutches are thought to aid the compaction of these domains. Here, we reconstituted TAD-sized chromatin fibers...
6.
Basak R, Yadav I, Arluison V, van Kan J, van der Maarel J
Methods Mol Biol
. 2022 Aug;
2538:305-317.
PMID: 35951308
Nanofluidics is an emerging methodology to investigate single biomacromolecules without functionalization and/or attachment of the molecules to a substrate. In conjunction with fluorescence microscopy, it can be used to investigate...
7.
Dai L, van der Maarel J, Doyle P
ACS Macro Lett
. 2022 May;
1(6):732-736.
PMID: 35607094
Monte Carlo simulations are used to study the knotting probability of circular DNA confined in a slit. We systematically vary the slit height, the width, and the contour length of...
8.
Dai L, Ng S, Doyle P, van der Maarel J
ACS Macro Lett
. 2022 May;
1(8):1046-1050.
PMID: 35607035
Currently, no theory is available to describe the conformation of DNA confined in a channel when the nanochannel diameter is around the persistence length. Back-folded hairpins in the undulating wormlike...
9.
Loke M, Yadav I, Lim T, van der Maarel J, Sham L, Chow V
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328711
The presence of co-infections or superinfections with bacterial pathogens in COVID-19 patients is associated with poor outcomes, including increased morbidity and mortality. We hypothesized that SARS-CoV-2 and its components interact...
10.
Tan C, Basak R, Yadav I, van Kan J, Arluison V, van der Maarel J
J Phys Chem B
. 2022 Feb;
126(7):1477-1482.
PMID: 35166115
The mobility of protein is fundamental in the machinery of life. Here, we have investigated the effect of DNA binding in conjunction with DNA segmental fluctuation (internal motion) of the...