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Johan Ericson

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Recent Articles
1.
Alekseenko Z, Dias J, Adler A, Kozhevnikova M, van Lunteren J, Nolbrant S, et al.
Nat Commun . 2022 Jun; 13(1):3046. PMID: 35650213
Stem cell therapies for Parkinson's disease (PD) have entered first-in-human clinical trials using a set of technically related methods to produce mesencephalic dopamine (mDA) neurons from human pluripotent stem cells...
2.
Dias J, Alekseenko Z, Jeggari A, Boareto M, Vollmer J, Kozhevnikova M, et al.
Sci Adv . 2020 Sep; 6(38). PMID: 32938678
How time is measured by neural stem cells during temporal neurogenesis has remained unresolved. By combining experiments and computational modeling, we define a Shh/Gli-driven three-node timer underlying the sequential generation...
3.
Klum S, Zaouter C, Alekseenko Z, Bjorklund A, Hagey D, Ericson J, et al.
EMBO Rep . 2018 Sep; 19(11). PMID: 30166336
SOX transcription factors have important roles during astrocyte and oligodendrocyte development, but how glial genes are specified and activated in a sub-lineage-specific fashion remains unknown. Here, we define glial-specific gene...
4.
Jeggari A, Alekseenko Z, Petrov I, Dias J, Ericson J, Alexeyenko A
Nucleic Acids Res . 2018 Jun; 46(W1):W163-W170. PMID: 29893885
The new web resource EviNet provides an easily run interface to network enrichment analysis for exploration of novel, experimentally defined gene sets. The major advantages of this analysis are (i)...
5.
Hoelzl M, Heby-Henricson K, Gerling M, Dias J, Kuiper R, Trunkle C, et al.
Dev Biol . 2017 Jul; 429(1):132-146. PMID: 28688895
Suppressor of Fused (SUFU) is an essential negative regulator of the Hedgehog (HH) pathway and involved in GLI transcription factor regulation. Due to early embryonic lethality of Sufu mice, investigations...
6.
Doucet-Beaupre H, Gilbert C, Schaan Profes M, Chabrat A, Pacelli C, Giguere N, et al.
Proc Natl Acad Sci U S A . 2016 Jul; 113(30):E4387-96. PMID: 27407143
The LIM-homeodomain transcription factors Lmx1a and Lmx1b play critical roles during the development of midbrain dopaminergic progenitors, but their functions in the adult brain remain poorly understood. We show here...
7.
Gross S, Garofalo D, Balderes D, Mastracci T, Dias J, Perlmann T, et al.
Development . 2016 Jun; 143(14):2616-28. PMID: 27287799
Intestinal hormone-producing cells represent the largest endocrine system in the body, but remarkably little is known about enteroendocrine cell type specification in the embryo and adult. We analyzed stage- and...
8.
Hedlund E, Belnoue L, Theofilopoulos S, Salto C, Bye C, Parish C, et al.
Sci Rep . 2016 Jun; 6:26448. PMID: 27246266
Degeneration of dopamine neurons in the midbrain causes symptoms of the movement disorder, Parkinson disease. Dopamine neurons are generated from proliferating progenitor cells localized in the embryonic ventral midbrain. However,...
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Jarrar W, Dias J, Ericson J, Arnold H, Holz A
PLoS One . 2015 Apr; 10(4):e0124408. PMID: 25919494
Cranial motor nerves in vertebrates are comprised of the three principal subtypes of branchial, visceral, and somatic motor neurons, which develop in typical patterns along the anteroposterior and dorsoventral axes...