Joern E Schmitz
Overview
Explore the profile of Joern E Schmitz including associated specialties, affiliations and a list of published articles.
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31
Citations
1545
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Recent Articles
1.
Conley H, He M, Easterhoff D, Kirshner H, Cocklin S, Meyer J, et al.
Front Immunol
. 2024 Jan;
14:1306292.
PMID: 38264644
Fcγ receptors (FcγRs) are membrane-bound glycoproteins that bind to the fragment crystallizable (Fc) constant regions of IgG antibodies. Interactions between IgG immune complexes and FcγRs can initiate signal transduction that...
2.
Wilmschen S, Schmitz J, Kimpel J
Vaccines (Basel)
. 2019 Sep;
7(3).
PMID: 31546894
Extensive research on generating an efficient HIV vaccine is ongoing. A major aim of HIV vaccines is the induction of long-lasting, broadly neutralizing antibodies (bnAbs) that can confer sterile immunity...
3.
Bresk C, Hofer T, Wilmschen S, Krismer M, Beierfuss A, Effantin G, et al.
Viruses
. 2019 Feb;
11(2).
PMID: 30769947
A chimeric vesicular stomatitis virus with the glycoprotein of the lymphocytic choriomeningitis virus, VSV-GP, is a potent viral vaccine vector that overcomes several of the limitations of wild-type VSV. Here,...
4.
Boesch A, Osei-Owusu N, Crowley A, Chu T, Chan Y, Weiner J, et al.
Front Immunol
. 2016 Dec;
7:589.
PMID: 28018355
Antibodies raised in Indian rhesus macaques [ (MM)] in many preclinical vaccine studies are often evaluated for titer, antigen-recognition breadth, neutralization potency, and/or effector function, and for potential associations with...
5.
Cartwright E, Spicer L, Smith S, Lee D, Fast R, Paganini S, et al.
Immunity
. 2016 Sep;
45(3):656-668.
PMID: 27653601
Infection with HIV persists despite suppressive antiretroviral therapy (ART), and treatment interruption results in rapid viral rebound. Antibody-mediated CD8(+) lymphocyte depletion in simian immunodeficiency virus (SIV)-infected rhesus macaques (RMs) shows...
6.
Keating S, Heitman J, Wu S, Deng X, Stacey A, Zahn R, et al.
J Virol
. 2016 Sep;
90(22):10339-10350.
PMID: 27630228
Importance: NHP models of HIV infection constitute a powerful tool with which to study viral pathogenesis in order to gain critical information for a better understanding of HIV infection in...
7.
Chan Y, Boesch A, Osei-Owusu N, Emileh A, Crowley A, Cocklin S, et al.
J Immunol
. 2016 Aug;
197(7):2936-47.
PMID: 27559046
Indian rhesus macaques (Macaca mulatta) are routinely used in preclinical studies to evaluate therapeutic Abs and candidate vaccines. The efficacy of these interventions in many cases is known to rely...
8.
Santra S, Tomaras G, Warrier R, Nicely N, Liao H, Pollara J, et al.
PLoS Pathog
. 2015 Aug;
11(8):e1005042.
PMID: 26237403
HIV-1 mucosal transmission begins with virus or virus-infected cells moving through mucus across mucosal epithelium to infect CD4+ T cells. Although broadly neutralizing antibodies (bnAbs) are the type of HIV-1...
9.
Chowdhury A, Hayes T, Bosinger S, Lawson B, Vanderford T, Schmitz J, et al.
J Virol
. 2015 Jun;
89(17):8677-86.
PMID: 26063417
Unlabelled: Numerous studies have demonstrated that CD8(+) T lymphocytes suppress virus replication during human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) infection. However, the mechanisms underlying this activity of T cells...
10.
Gombos R, Kolodkin-Gal D, Eslamizar L, Owuor J, Mazzola E, Gonzalez A, et al.
J Virol
. 2015 May;
89(15):7813-28.
PMID: 25995259
Unlabelled: To date, most therapeutic and vaccine candidates for human immunodeficiency virus type 1 (HIV-1) are evaluated preclinically for efficacy against cell-free viral challenges. However, cell-associated HIV-1 is suggested to...