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Joerg Ruschel

Explore the profile of Joerg Ruschel including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 19
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Recent Articles
1.
Mulder I, Abbinanti M, Woller S, Ruschel J, Coutinho J, de Vries H, et al.
J Cereb Blood Flow Metab . 2024 Jun; 44(11):1238-1252. PMID: 38833563
Endothelial blood-brain barrier (BBB) dysfunction is critical in the pathophysiology of brain injury. Rho-associated protein kinase (ROCK) activation disrupts BBB integrity in the injured brain. We aimed to test the...
2.
Woller S, Ruschel J, Morquette B, Cardia J, Yan D, Holton K, et al.
iScience . 2022 May; 25(6):104379. PMID: 35620420
The therapeutic use of RNAi has grown but often faces several hurdles related to delivery systems, compound stability, immune activation, and on-target/off-tissue effects. Self-delivering RNAi (sdRNA) molecules do not require...
3.
McKerracher L, Shenkar R, Abbinanti M, Cao Y, Peiper A, Liao J, et al.
Transl Stroke Res . 2019 Aug; 11(3):365-376. PMID: 31446620
Cavernous angioma (CA) is a vascular pathology caused by loss of function in one of the 3 CA genes (CCM1, CCM2, and CCM3) that result in rho kinase (ROCK) activation....