Joel D Mainland
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Explore the profile of Joel D Mainland including associated specialties, affiliations and a list of published articles.
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36
Citations
1200
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Recent Articles
1.
Hamel E, Castro J, Gould T, Pellegrino R, Liang Z, Coleman L, et al.
Sci Data
. 2024 Nov;
11(1):1220.
PMID: 39532906
Advances in theoretical understanding are frequently unlocked by access to large, diverse experimental datasets. Our understanding of olfactory neuroscience and psychophysics remain years behind the other senses, in part because...
2.
Kamarck M, Trimmer C, Murphy N, Gregory K, Manoel D, Logan D, et al.
Clin Genet
. 2023 Dec;
105(4):376-385.
PMID: 38148624
An estimated 1 in 10 000 people are born without the ability to smell, a condition known as congenital anosmia, and about one third of those people have non-syndromic, or...
3.
Mennella J, Kan M, Lowenthal E, Saraiva L, Mainland J, Himes B, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685855
There is wide variation in how individuals perceive the chemosensory attributes of liquid formulations of ibuprofen, encompassing both adults and children. To understand personal variation in the taste and chemesthesis...
4.
Lee B, Mayhew E, Sanchez-Lengeling B, Wei J, Qian W, Little K, et al.
Science
. 2023 Aug;
381(6661):999-1006.
PMID: 37651511
Mapping molecular structure to odor perception is a key challenge in olfaction. We used graph neural networks to generate a principal odor map (POM) that preserves perceptual relationships and enables...
5.
Novaleski C, Hegland K, Aleksandruk M, Dalton P, Mainland J
Am J Speech Lang Pathol
. 2023 Jan;
32(2):675-687.
PMID: 36634229
Purpose: Methods for cough elicitation frequently involve aerosolized tussive agents. Here, we sought to determine whether healthy individuals demonstrate a quantifiable cough response after inhaling a volatile ester and if...
6.
Sato-Akuhara N, Trimmer C, Keller A, Niimura Y, Shirasu M, Mainland J, et al.
Chem Senses
. 2023 Jan;
48.
PMID: 36625229
Humans have significant individual variations in odor perception, derived from their experience or sometimes from differences in the olfactory receptor (OR) gene repertoire. In several cases, the genetic variation of...
7.
Arshamian A, Gerkin R, Kruspe N, Wnuk E, Floyd S, OMeara C, et al.
Curr Biol
. 2022 Apr;
32(9):2061-2066.e3.
PMID: 35381183
Humans share sensory systems with a common anatomical blueprint, but individual sensory experience nevertheless varies. In olfaction, it is not known to what degree sensory perception, particularly the perception of...
8.
Mayhew E, Arayata C, Gerkin R, Lee B, Magill J, Snyder L, et al.
Proc Natl Acad Sci U S A
. 2022 Apr;
119(15):e2116576119.
PMID: 35377807
In studies of vision and audition, stimuli can be chosen to span the visible or audible spectrum; in olfaction, the axes and boundaries defining the analogous odorous space are unknown....
9.
Ruiz Tejada Segura M, Moussa E, Garabello E, Nakahara T, Makhlouf M, Mathew L, et al.
Cell Rep
. 2022 Mar;
38(12):110547.
PMID: 35320714
The sense of smell helps us navigate the environment, but its molecular architecture and underlying logic remain understudied. The spatial location of odorant receptor genes (Olfrs) in the nose is...
10.
Li B, Kamarck M, Peng Q, Lim F, Keller A, Smeets M, et al.
PLoS Genet
. 2022 Feb;
18(2):e1009564.
PMID: 35113854
The olfactory system combines input from multiple receptor types to represent odor information, but there are few explicit examples relating olfactory receptor (OR) activity patterns to odor perception. To uncover...