Joel D Baines
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Explore the profile of Joel D Baines including associated specialties, affiliations and a list of published articles.
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62
Citations
2479
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Recent Articles
1.
Birkenheuer C, Baines J
J Virol
. 2024 May;
98(6):e0071224.
PMID: 38780246
Within the first 15 minutes of infection, herpes simplex virus 1 immediate early proteins repurpose cellular RNA polymerase (Pol II) for viral transcription. An important role of the viral-infected cell...
2.
Dunn L, Birkenheuer C, Baines J
Microorganisms
. 2024 Feb;
12(2).
PMID: 38399666
The herpes virus genome bears more than 80 strong transcriptional promoters. Upon entry into the host cell nucleus, these genes are transcribed in an orderly manner, producing five immediate-early (IE)...
3.
Dunn L, Baines J
J Virol
. 2023 Sep;
97(10):e0096023.
PMID: 37754762
Infection with herpes simplex virus 1 (HSV-1) leads to lifelong infection due to the virus's remarkable ability to control transcription of its own genome, resulting in two transcriptional programs: lytic...
4.
Dunn L, Lu F, Su C, Lieberman P, Baines J
J Virol
. 2023 Feb;
97(2):e0189422.
PMID: 36744959
The ability of Epstein-Barr virus (EBV) to switch between latent and lytic infection is key to its long-term persistence, yet the molecular mechanisms behind this switch remain unclear. To investigate...
5.
Dunn L, Birkenheuer C, Dufour R, Baines J
J Virol
. 2022 Oct;
96(22):e0141622.
PMID: 36300939
Herpes simplex virus 1 (HSV-1) utilizes cellular RNA polymerase II (Pol) to transcribe its genes in one of two phases. In the latent phase, viral transcription is highly restricted, but...
6.
Birkenheuer C, Dunn L, Dufour R, Baines J
J Virol
. 2022 Jan;
96(5):e0219121.
PMID: 35019725
To determine the role of ICP22 in transcription, we performed precise nuclear run-on followed by deep sequencing (PRO-seq) and global nuclear run-on with sequencing (GRO-seq) in cells infected with a...
7.
Birkenheuer C, Baines J
J Virol
. 2019 Dec;
94(5).
PMID: 31826988
Herpes simplex virus 1 (HSV-1) genes are transcribed by cellular RNA polymerase II (Pol II). Expression of viral immediate early (α) genes is followed sequentially by early (β), late (γ),...
8.
Farkas T, Yang K, Le Pendu J, Baines J, Cardin R
J Virol
. 2019 Sep;
93(22).
PMID: 31484750
Human norovirus (HuNoV) is a leading cause of acute gastroenteritis in both developed and developing countries. Studies of HuNoV host cell interactions are limited by the lack of a simple,...
9.
Pennington M, Voorhees I, Callaway H, Dehghanpir S, Baines J, Parrish C, et al.
J Virol
. 2018 Jul;
92(20).
PMID: 30045987
Alphaherpesvirus-associated ocular infections in humans caused by human alphaherpesvirus 1 (HHV-1) remain challenging to treat due to the frequency of drug application required and the potential for the selection of...
10.
Birkenheuer C, Danko C, Baines J
J Virol
. 2018 Feb;
92(8).
PMID: 29437966
Herpes simplex virus 1 (HSV-1) transcription is mediated by cellular RNA polymerase II (Pol II). Recent studies investigating how Pol II transcription of host genes is altered after HSV-1 are...