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Joel C Bornstein

Explore the profile of Joel C Bornstein including associated specialties, affiliations and a list of published articles. Areas
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Articles 87
Citations 1860
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Recent Articles
11.
Poon S, Hung L, Wu Q, Parathan P, Yalcinkaya N, Haag A, et al.
J Physiol . 2022 Sep; 600(19):4303-4323. PMID: 36082768
Infants and young children receive the highest exposures to antibiotics globally. Although there is building evidence that early life exposure to antibiotics increases susceptibility to various diseases including gut disorders...
12.
Filippone R, Dargahi N, Eri R, Uranga J, Bornstein J, Apostolopoulos V, et al.
Int J Mol Sci . 2022 Jul; 23(14). PMID: 35887133
Eosinophils and their regulatory molecules have been associated with chronic intestinal inflammation and gastrointestinal dysfunctions; eosinophil accumulation in the gut is prominent in inflammatory bowel disease (IBD). The chemokine receptor...
13.
Eskikand P, Koussoulas K, Gwynne R, Bornstein J
PLoS Comput Biol . 2022 Jun; 18(6):e1009717. PMID: 35696419
Transmission between neurons in the extensive enteric neural networks of the gut involves synaptic potentials with vastly different time courses and underlying conductances. Most enteric neurons exhibit fast excitatory post-synaptic...
14.
Stavely R, Rahman A, Sahakian L, Prakash M, Robinson A, Hassanzadeganroudsari M, et al.
Inflamm Bowel Dis . 2022 Apr; 28(8):1229-1243. PMID: 35380670
Background: The autonomic nervous system (ANS) is thought to play a critical role in the anti-inflammatory reflex pathway in acute colitis via its interaction with the spleen and colon. Inflammation...
15.
Craig C, Filippone R, Stavely R, Bornstein J, Apostolopoulos V, Nurgali K
J Neuroinflammation . 2022 Jan; 19(1):4. PMID: 34983592
Patients with inflammatory bowel disease (IBD) suffer from depression at higher rates than the general population. An etiological trigger of depressive symptoms is theorised to be inflammation within the central...
16.
Balasuriya G, Nugapitiya S, Hill-Yardin E, Bornstein J
Front Neurosci . 2021 Oct; 15:647555. PMID: 34658750
Women are more susceptible to functional bowel disorders than men and the severity of their symptoms such as diarrhea, constipation, abdominal pain and bloating changes over the menstrual cycle, suggesting...
17.
Wang H, Foong J, Harris N, Bornstein J
Mucosal Immunol . 2021 Oct; 15(1):188. PMID: 34593981
No abstract available.
18.
Wang H, Foong J, Harris N, Bornstein J
Mucosal Immunol . 2021 Sep; 15(1):27-39. PMID: 34471248
The enteric nervous system (ENS) of the gastrointestinal (GI) tract interacts with the local immune system bidirectionally. Recent publications have demonstrated that such interactions can maintain normal GI functions during...
19.
Wright C, Schneider S, Smith-Edwards K, Mafra F, Leembruggen A, Gonzalez M, et al.
Cell Mol Gastroenterol Hepatol . 2021 Jan; 11(5):1548-1592.e1. PMID: 33444816
Background And Aims: Bowel function requires coordinated activity of diverse enteric neuron subtypes. Our aim was to define gene expression in these neuron subtypes to facilitate development of novel therapeutic...
20.
Foong J, Hung L, Poon S, Savidge T, Bornstein J
Am J Physiol Gastrointest Liver Physiol . 2020 Sep; 319(5):G541-G548. PMID: 32902314
Recent studies on humans and their key experimental model, the mouse, have begun to uncover the importance of gastrointestinal (GI) microbiota and enteric nervous system (ENS) interactions during developmental windows...