Joel Abramowitz
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Explore the profile of Joel Abramowitz including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Kochukov M, Balasubramanian A, Abramowitz J, Birnbaumer L, Marrelli S
J Am Heart Assoc
. 2014 Aug;
3(4).
PMID: 25142058
Background: Transient receptor potential C3 (TRPC3) has been demonstrated to be involved in the regulation of vascular tone through endothelial cell (EC) hyperpolarization and endothelium-dependent hyperpolarization-mediated vasodilation. However, the mechanism...
12.
Phelan K, Shwe U, Abramowitz J, Birnbaumer L, Zheng F
Proc Natl Acad Sci U S A
. 2014 Jul;
111(31):11533-8.
PMID: 25049394
Status epilepticus (SE) is a life-threatening disease that has been recognized since antiquity but still causes over 50,000 deaths annually in the United States. The prevailing view on the pathophysiology...
13.
Liao Y, Abramowitz J, Birnbaumer L
Handb Exp Pharmacol
. 2014 Jun;
223:1055-75.
PMID: 24961980
Aside from entering into cells through voltage gated Ca channels and Na/Ca exchangers in those cells that express these proteins, for all cells be they excitable or non-excitable, Ca(2+) enters...
14.
Xia Y, Yang X, Fu Z, Paudel O, Abramowitz J, Birnbaumer L, et al.
Hypertension
. 2013 Oct;
63(1):173-80.
PMID: 24144647
Hypoxic pulmonary hypertension is characterized by increased vascular tone, altered vasoreactivity, and vascular remodeling, which are associated with alterations in Ca(2+) homeostasis in pulmonary arterial smooth muscle cells. We have...
15.
Feng S, Li H, Tai Y, Huang J, Su Y, Abramowitz J, et al.
Proc Natl Acad Sci U S A
. 2013 Jun;
110(27):11011-6.
PMID: 23776229
Mitochondrial Ca(2+) homeostasis is fundamental to regulation of mitochondrial membrane potential, ATP production, and cellular Ca(2+) homeostasis. It has been known for decades that isolated mitochondria can take up Ca(2+)...
16.
Ong E, Nesin V, Long C, Bai C, Guz J, Ivanov I, et al.
J Biol Chem
. 2013 Jun;
288(31):22219-32.
PMID: 23770672
Ca(2+) signaling is essential for bone homeostasis and skeletal development. Here, we show that the transient receptor potential canonical 1 (TRPC1) channel and the inhibitor of MyoD family, I-mfa, function...
17.
Sebastian S, Ang R, Abramowitz J, Weinstein L, Chen M, Ludwig A, et al.
Am J Physiol Regul Integr Comp Physiol
. 2013 May;
305(4):R435-42.
PMID: 23697798
Reciprocal physiological modulation of heart rate is controlled by the sympathetic and parasympathetic systems acting on the sinoatrial (SA) node. However, there is little direct in vivo work examining the...
18.
Dasari S, Abramowitz J, Birnbaumer L, Gulledge A
Neuroreport
. 2013 May;
24(10):550-4.
PMID: 23652155
Activation of M1-type muscarinic acetylcholine receptors excites neocortical pyramidal neurons, in part by gating a nonselective cation conductance that produces calcium-dependent 'afterdepolarizing potentials' (ADPs) following short trains of action potentials....
19.
Medic N, Desai A, Olivera A, Abramowitz J, Birnbaumer L, Beaven M, et al.
Cell Calcium
. 2013 Mar;
53(5-6):315-26.
PMID: 23489970
Antigen-mediated mast cell (MC) degranulation is the critical early event in the induction of allergic reactions. Transient receptor potential channels (TRPC), particularly TRPC1, are thought to contribute to such MC...
20.
Yeo M, Berglund K, Hanna M, Guo J, Kittur J, Torres M, et al.
Proc Natl Acad Sci U S A
. 2013 Feb;
110(11):4315-20.
PMID: 23440186
Bisphenol A (BPA) is a ubiquitous compound that is emerging as a possible toxicant during embryonic development. BPA has been shown to epigenetically affect the developing nervous system, but the...