Jody V Vykoukal
Overview
Explore the profile of Jody V Vykoukal including associated specialties, affiliations and a list of published articles.
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20
Citations
431
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Recent Articles
1.
Fan Y, Song S, Pizzi M, Zou G, Vykoukal J, Yoshimura K, et al.
iScience
. 2025 Jan;
28(1):111564.
PMID: 39811647
Peritoneal carcinomatosis (PC) in gastric adenocarcinoma (GAC) is the most common metastatic site and leads to a short median survival. Exosomes have been shown to remodel the microenvironment, facilitating tumor...
2.
Song L, Irajizad E, Rundle A, Sesso H, Gaziano J, Vykoukal J, et al.
Cancers (Basel)
. 2024 Jun;
16(11).
PMID: 38893188
This study aimed to assess a four-marker protein panel (4MP)'s performance, including the precursor form of surfactant protein B, cancer antigen 125, carcinoembryonic antigen, and cytokeratin-19, for predicting lung cancer...
3.
Geng C, Zhang M, Manyam G, Vykoukal J, Fahrmann J, Peng S, et al.
Clin Cancer Res
. 2023 Aug;
29(21):4464-4478.
PMID: 37581614
Purpose: Speckle-type POZ protein (SPOP) is important in DNA damage response (DDR) and maintenance of genomic stability. Somatic heterozygous missense mutations in the SPOP substrate-binding cleft are found in up...
4.
Leon-Letelier R, Abdel Sater A, Chen Y, Park S, Wu R, Irajizad E, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765792
The nuclear factor erythroid 2-related factor 2 (NRF2) pathway is frequently activated in various cancer types. Aberrant activation of NRF2 in cancer is attributed to gain-of-function mutations in the NRF2-encoding...
5.
Fahrmann J, Tanaka I, Irajizad E, Mao X, Dennison J, Murage E, et al.
Cancers (Basel)
. 2022 May;
14(10).
PMID: 35626147
Activation of the NRF2 pathway through gain-of-function mutations or loss-of-function of its suppressor KEAP1 is a frequent finding in lung cancer. NRF2 activation has been reported to alter the tumor...
6.
Capello M, Fahrmann J, Rios Perez M, Vykoukal J, Irajizad E, Tripathi S, et al.
JCO Precis Oncol
. 2022 Jan;
4:426-436.
PMID: 35050739
Purpose: The combination chemotherapy of fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) has provided clinically meaningful improvement for pancreatic ductal adenocarcinoma (PDAC). We previously uncovered a role for the serine hydrolase...
7.
Chen Y, Capello M, Rios Perez M, Vykoukal J, Roife D, Kang Y, et al.
Mol Metab
. 2021 Dec;
56:101426.
PMID: 34971802
Objective: Intra-tumoral expression of the serine hydrolase carboxylesterase 2 (CES2) contributes to the activation of the pro-drug irinotecan in pancreatic ductal adenocarcinoma (PDAC). Given other potential roles of CES2, we...
8.
Kato T, Vykoukal J, Fahrmann J, Hanash S
Cancers (Basel)
. 2021 Sep;
13(18).
PMID: 34572829
Extracellular vesicles (EVs) are nano-sized lipid-bound particles containing proteins, nucleic acids and metabolites released by cells. They have been identified in body fluids including blood, saliva, sputum and pleural effusions....
9.
Tripathi S, Fahrmann J, Vykoukal J, Dennison J, Hanash S
Cancer Rep (Hoboken)
. 2020 Jul;
2(1):e1131.
PMID: 32721114
Background: Altered cell metabolism is an established hallmark of cancer. Advancement in our understanding of dysregulated cellular metabolism has aided drastically in identifying metabolic vulnerabilities that can be exploited therapeutically....
10.
Vykoukal J, Fahrmann J, Thompson T
Cancer Metastasis Rev
. 2020 May;
39(2):341-342.
PMID: 32417992
No abstract available.