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Jodie R Malcolm

Explore the profile of Jodie R Malcolm including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Malcolm J, Bridge K, Holding A, Brackenbury W
BMC Genomics . 2025 Jan; 26(1):59. PMID: 39838295
Hypoxia is common in breast tumours and is linked to therapy resistance and advanced disease. To understand hypoxia-driven breast cancer progression, RT-qPCR is a widely used technique to quantify transcriptional...
2.
Capatina A, Malcolm J, Stenning J, Moore R, Bridge K, Brackenbury W, et al.
Front Cell Dev Biol . 2024 Sep; 12:1421629. PMID: 39282472
The events that control breast cancer progression and metastasis are complex and intertwined. Hypoxia plays a key role both in oncogenic transformation and in fueling the metastatic potential of breast...
3.
Malcolm J, Sajjaboontawee N, Yerlikaya S, Plunkett-Jones C, Boxall P, Brackenbury W
Curr Top Membr . 2023 Nov; 92:71-98. PMID: 38007270
Sodium (Na) concentration in solid tumours of different origin is highly dysregulated, and this corresponds to the aberrant expression of Na transporters. In particular, the α subunits of voltage gated...
4.
Malcolm J, Leese N, Lamond-Warner P, Brackenbury W, White R
Gene . 2022 Feb; 821:146280. PMID: 35143945
tRNA gene transcription by RNA polymerase III (Pol III) is a tightly regulated process, but dysregulated Pol III transcription is widely observed in cancers. Approximately 75% of all breast cancers...
5.
Guo X, Malcolm J, Ali M, Morais G, Shnyder S, Loadman P, et al.
Analyst . 2020 May; 145(13):4512-4521. PMID: 32412559
The polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology...