Jochen Wilhelm
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Explore the profile of Jochen Wilhelm including associated specialties, affiliations and a list of published articles.
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Articles
166
Citations
3482
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Recent Articles
1.
Birnhuber A, Biasin V, Jain P, Kwiatkowski G, Boiarina E, Wilhelm J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2025 Feb;
328(3):L413-L429.
PMID: 39903186
Lung vessel remodeling leads to increased pulmonary vascular resistance, causing pulmonary arterial hypertension (PAH), and consequently right ventricular hypertrophy and failure. In patients suffering from systemic sclerosis (SSc), PAH can...
2.
Leib L, Juli J, Jurida L, Mayr-Buro C, Priester J, Weiser H, et al.
EMBO Rep
. 2025 Jan;
26(4):1144-1183.
PMID: 39753783
The protein interactome of p65/RELA, the most active subunit of the transcription factor (TF) NF-κB, has not been previously determined in living cells. Using p65-miniTurbo fusion proteins and biotin tagging,...
3.
Madan E, Palma A, Vudatha V, Kumar A, Bhoopathi P, Wilhelm J, et al.
Nat Biotechnol
. 2024 Dec;
PMID: 39653752
Cell competition and fitness comparison between cancer and tumor microenvironment (TME) cells determine oncogenic fate. Our previous study established a role for human Flower isoforms as fitness fingerprints, where the...
4.
Potaczek D, van Tol B, Falck D, Krolczik C, Zlatina K, Bertrams W, et al.
Front Immunol
. 2024 Nov;
15:1439248.
PMID: 39512344
Thromboembolic complications are common in severe COVID-19 and are thought to result from excessive neutrophil-extracellular-trap (NET)-driven immunothrombosis. Glycosylation plays a vital role in the efficiency of immunoglobulin A (IgA) effector...
5.
Gellhorn Serra M, Meier L, Sauerhering L, Wilhelm J, Kupke A
J Gen Virol
. 2024 Oct;
105(10).
PMID: 39466030
Nipah virus (NiV) and Ebola virus (EBOV) are highly pathogenic zoonotic viruses with case fatality rates of up to 90%. While the brain is a known target organ following NiV...
6.
Lingampally A, Truchi M, Mauduit O, Delcroix V, Vasquez-Pacheco E, Gautier-Isola M, et al.
Eur Respir J
. 2024 Oct;
65(2).
PMID: 39401861
Background: Fibrosis is often associated with aberrant repair mechanisms that ultimately lead to organ failure. In the lung, idiopathic pulmonary fibrosis (IPF) is a fatal form of interstitial lung disease...
7.
Senescence of lung mesenchymal stem cells of preterm infants by cyclic stretch and hyperoxia via p21
Behnke J, Goetz M, Holzfurtner L, Korte P, Weiss A, Shahzad T, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Sep;
327(5):L694-L711.
PMID: 39316679
Phenotype distortion of lung resident mesenchymal stem cells (MSC) in preterm infants is a hallmark event in the pathogenesis of bronchopulmonary dysplasia (BPD). Here, we evaluated the impact of cyclic...
8.
Hofmann N, Bartkuhn M, Becker S, Biedenkopf N, Bottcher-Friebertshauser E, Brinkrolf K, et al.
J Virol
. 2024 Sep;
98(10):e0093524.
PMID: 39283124
The large group of negative-strand RNA viruses (NSVs) comprises many important pathogens. To identify conserved patterns in host responses, we systematically compared changes in the cellular RNA levels after infection...
9.
Tello K, Yogeswaran A, Majeed R, Kiely D, Lawrie A, Brittain E, et al.
Chest
. 2024 Aug;
167(1):224-240.
PMID: 39182575
Background: Patients with COPD frequently demonstrate pulmonary hypertension (PH). Severe PH in patients with COPD, identified by pulmonary vascular resistance (PVR) of > 5 Wood units (WU), is closely linked...
10.
Cekay M, Arndt P, Franken J, Wilhelm J, Pullamsetti S, Roller F, et al.
BMJ Open Respir Res
. 2024 Aug;
11(1).
PMID: 39179271
Background: Cancer is one of the leading causes of death worldwide, and cardiopulmonary comorbidities may further adversely affect cancer prognosis. We recently described lung cancer-associated pulmonary hypertension (PH) as a...