Jochen S Hub
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Explore the profile of Jochen S Hub including associated specialties, affiliations and a list of published articles.
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91
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2620
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Recent Articles
1.
Starke L, Allolio C, Hub J
PNAS Nexus
. 2025 Mar;
4(3):pgaf033.
PMID: 40046002
The primary function of biological membranes is to enable compartmentalization among cells and organelles. Loss of integrity by the formation of membrane pores would trigger uncontrolled depolarization or influx of...
2.
Vernuccio R, Martinez Leon A, Poojari C, Buchrieser J, Selverian C, Jaleta Y, et al.
Nat Microbiol
. 2025 Feb;
10(3):734-748.
PMID: 39939832
Mpox is a zoonotic disease endemic to Central and West Africa. Since 2022, two human-adapted monkeypox virus (MPXV) strains have caused large outbreaks outside these regions. Tecovirimat is the most...
3.
Vernuccio R, Martinez Leon A, Poojari C, Buchrieser J, Selverian C, Jaleta Y, et al.
Res Sq
. 2024 Oct;
PMID: 39399667
Mpox is a zoonotic disease endemic in central and west Africa. However, since 2022, human-adapted mpox virus (MPXV) strains are causing large outbreaks spreading outside these regions, leading the World...
4.
Lee S, Poojari C, Maznichenko A, Roesel D, Swiderska I, Pohl P, et al.
J Am Chem Soc
. 2024 Jul;
146(29):19818-19827.
PMID: 38991220
Proton translocation through lipid membranes is a fundamental process in the field of biology. Several theoretical models have been developed and presented over the years to explain the phenomenon, yet...
5.
Dhiman R, Perera R, Poojari C, Wiedemann H, Kappl R, Kay C, et al.
Nat Commun
. 2024 May;
15(1):4504.
PMID: 38802378
Lipid droplet (LD) function relies on proteins partitioning between the endoplasmic reticulum (ER) phospholipid bilayer and the LD monolayer membrane to control cellular adaptation to metabolic changes. It has been...
6.
Kasparyan G, Hub J
Phys Rev Lett
. 2024 Apr;
132(14):148401.
PMID: 38640376
The formation of pores over lipid membranes by the application of electric fields, termed membrane electroporation, is widely used in biotechnology and medicine to deliver drugs, vaccines, or genes into...
7.
Marasco M, Kirkpatrick J, Carlomagno T, Hub J, Anselmi M
Comput Struct Biotechnol J
. 2024 Mar;
23:1169-1180.
PMID: 38510972
SHP2 is a tyrosine phosphatase that plays a regulatory role in multiple intracellular signaling cascades and is known to be oncogenic in certain contexts. In the absence of effectors, SHP2...
8.
Anselmi M, Hub J
Commun Biol
. 2023 Dec;
6(1):1289.
PMID: 38129686
SHP2 phosphatase plays an important role in regulating several intracellular signaling pathways. Pathogenic mutations of SHP2 cause developmental disorders and are linked to hematological malignancies and cancer. SHP2 comprises two...
9.
Linse J, Hub J
Commun Chem
. 2023 Dec;
6(1):272.
PMID: 38086909
Biological macromolecules in solution are surrounded by a hydration shell, whose structure differs from the structure of bulk solvent. While the importance of the hydration shell for numerous biological functions...
10.
Molecular Simulations of Liquid Jet Explosions and Shock Waves Induced by X-Ray Free-Electron Lasers
Chatzimagas L, Hub J
Phys Rev Lett
. 2023 Oct;
131(13):134003.
PMID: 37832003
X-ray free-electron lasers (XFELs) produce x-ray pulses with high brilliance and short pulse duration. These properties enable structural investigations of biomolecular nanocrystals, and they allow one to resolve the dynamics...