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Jochen C Rink

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Articles 38
Citations 1689
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Recent Articles
1.
Gasiorowski L, Chai C, Rozanski A, Purandare G, Ficze F, Mizi A, et al.
Nat Commun . 2025 Jan; 16(1):1232. PMID: 39890822
The remarkable regenerative abilities of flatworms are closely linked to neoblasts - adult pluripotent stem cells that are the only division-competent cell type outside of the reproductive system. Although the...
2.
Ivankovic M, Brand J, Pandolfini L, Brown T, Pippel M, Rozanski A, et al.
Nat Commun . 2024 Sep; 15(1):8215. PMID: 39294119
The planarian Schmidtea mediterranea is being studied as a model species for regeneration, but the assembly of planarian genomes remains challenging. Here, we report a high-quality haplotype-phased, chromosome-scale genome assembly...
3.
Lee J, Boothe T, Mauksch C, Thommen A, Rink J
Cell Rep . 2024 Jun; 43(7):114305. PMID: 38906148
Planarian flatworms undergo continuous internal turnover, wherein old cells are replaced by the division progeny of adult pluripotent stem cells (neoblasts). How cell turnover is carried out at the organismal...
4.
Gasiorowski L, Chai C, Rozanski A, Purandare G, Ficze F, Mizi A, et al.
bioRxiv . 2024 Jun; PMID: 38853907
The remarkable regenerative abilities of flatworms are closely linked to neoblasts - adult pluripotent stem cells that are the only division-competent cell type outside of the reproductive system. Although the...
5.
Gasiorowski L, Dittmann I, Brand J, Ruhwedel T, Mobius W, Egger B, et al.
BMC Biol . 2023 Nov; 21(1):266. PMID: 37993917
Background: Unlike most free-living platyhelminths, catenulids, the sister group to all remaining flatworms, do not have eyes. Instead, the most prominent sensory structures in their heads are statocysts or sensory...
6.
Vila-Farre M, Rozanski A, Ivankovic M, Cleland J, Brand J, Thalen F, et al.
Nat Ecol Evol . 2023 Oct; 7(12):2108-2124. PMID: 37857891
Regenerative abilities vary dramatically across animals. Even amongst planarian flatworms, well-known for complete regeneration from tiny body fragments, some species have restricted regeneration abilities while others are almost entirely regeneration...
7.
Weill U, Hall R, Drees L, Wang B, Rink J
Methods Mol Biol . 2023 Jul; 2680:263-275. PMID: 37428384
Planarians have become a powerful model system for stem cell research and regeneration. While the tool kit for mechanistic investigations has been steadily expanding over the last decade, robust genetic...
8.
Grohme M, Frank O, Rink J
Methods Mol Biol . 2023 Jul; 2680:121-155. PMID: 37428375
High-content fluorescence microscopy combines the efficiency of high-throughput techniques with the ability to extract quantitative information from biological systems. Here we describe a modular collection of assays adapted for fixed...
9.
Vila-Farre M, Vu H, Rink J
Methods Mol Biol . 2023 Jul; 2680:107-119. PMID: 37428374
Whole-mount in situ hybridization (WISH), colorimetric or fluorescent (FISH), allows for the visualization of endogenous RNA. For planarians, robust WISH protocols exist for small-sized animals (>5 mm) of the model...
10.
Boothe T, Ivankovic M, Grohme M, Markus M, Dullin C, Xu X, et al.
Commun Biol . 2023 May; 6(1):518. PMID: 37179375
Luminescent reporters are due to their intrinsically high signal-to-noise ratio a powerful labelling tool for microscopy and macroscopic in vivo imaging in biomedical research. However, luminescence signal detection requires longer...