Joao P B Viola
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Explore the profile of Joao P B Viola including associated specialties, affiliations and a list of published articles.
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53
Citations
1536
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Recent Articles
11.
Pastor T, Peixoto B, Viola J
Front Cell Dev Biol
. 2021 May;
9:655307.
PMID: 33996817
Interferon regulatory factor 2-binding protein 2 (IRF2BP2) encodes a member of the IRF2BP family of transcriptional regulators, which includes IRF2BP1, IRF2BP2, and IRF2BPL (EAP1). IRF2BP2 was initially identified as a...
12.
Siqueira J, Goes L, Alves B, de Carvalho P, Cicala C, Arthos J, et al.
Virus Evol
. 2021 Mar;
7(1):veab013.
PMID: 33738124
Numerous factors have been identified to influence susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and disease severity. Cancer patients are more prone to clinically evolve to more...
13.
Siqueira J, Goes L, Alves B, da Silva A, de Carvalho P, Cicala C, et al.
Infect Genet Evol
. 2021 Feb;
90:104772.
PMID: 33592317
Different groups have recently reported events of SARS-CoV-2 reinfection, where patients had a sequence of positive-negative-positive RT-PCR tests. However, such events could be explained by different scenarios such as intermittent...
14.
de Araujo W, Tanaka M, Lima P, de Moraes C, Leve F, Bastos L, et al.
Cell Biol Int
. 2020 Dec;
45(3):662-673.
PMID: 33300198
Transforming growth factor-β (TGF-β) plays a dual role acting as tumor promoter or suppressor. Along with cyclooxygenase-2 (COX-2) and oncogenic Ras, this multifunctional cytokine is deregulated in colorectal cancer. Despite...
15.
de Melo A, Thuler L, da Silva J, de Albuquerque L, Pecego A, Rodrigues L, et al.
PLoS One
. 2020 Oct;
15(10):e0241261.
PMID: 33104715
Objective: This study aimed to describe the demographic and clinical characteristics of cancer inpatients with COVID-19 exploring clinical outcomes. Methods: A retrospective search in the electronic medical records of cancer...
16.
Siqueira J, Goes L, Alves B, de Carvalho P, Cicala C, Arthos J, et al.
bioRxiv
. 2020 Sep;
PMID: 32869023
Author Summary: Cancer patients are more prone to clinically evolve to more severe COVID-19 conditions, but the determinants of such a more severe outcome remain largely unknown. In this study,...
17.
Delbue D, Mendonca B, Robaina M, Lemos L, Lucena P, Viola J, et al.
Biochim Biophys Acta Mol Cell Res
. 2020 Jun;
1867(10):118761.
PMID: 32485270
Evasion from apoptosis is one of the hallmarks of cancer. X-linked inhibitor of apoptosis protein (XIAP) is known to modulate apoptosis by inhibiting caspases and ubiquitinating target proteins. XIAP is...
18.
de Araujo-Souza P, Hanschke S, Nardy A, Secca C, Oliveira-Vieira B, Silva K, et al.
J Leukoc Biol
. 2020 May;
108(4):1329-1337.
PMID: 32421902
CD8 T cells play a crucial role in immune responses to virus infections and tumors. Naïve CD8 T lymphocytes after TCR stimulation undergo differentiation into CTLs and memory cells, which...
19.
Cruz A, Barreto E, Fazolini N, Viola J, Bozza P
Cell Death Dis
. 2020 Feb;
11(2):105.
PMID: 32029741
Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play important roles in cell signaling, lipid metabolism, membrane trafficking, and the production of inflammatory mediators. Lipid droplet...
20.
Benevides L, Saltarelli V, Pioto F, Sacramento L, Dias M, Rodriguez G, et al.
Front Immunol
. 2019 Sep;
10:2105.
PMID: 31555297
Monocytes play key roles in the maintenance of homeostasis and in the control of the infection. Monocytes are recruited from the bone marrow to inflammatory sites and are essential for...