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Joanne A de Hullu

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Articles 123
Citations 1307
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Recent Articles
1.
Fisch C, Gelderblom M, Hermens R, de Reuver P, Nienhuijs S, Somford D, et al.
BJS Open . 2025 Jan; 9(1). PMID: 39871731
Background: Ovarian cancer is the leading cause of death among gynaecological cancers. The identification of the fallopian tube epithelium as the origin of most ovarian cancers introduces a novel prevention...
2.
Van Bommel M, Steenbeek M, IntHout J, Van Garderen T, Harmsen M, Arts-De Jong M, et al.
BJOG . 2025 Jan; PMID: 39823150
Objective: To compare menopause-related quality of life (QoL) after risk-reducing salpingectomy (RRS) versus risk-reducing salpingo-oophorectomy (RRSO) until 3 years of post-surgery. Design: A prospective study (TUBA study) with treatment allocation...
3.
Beekman M, Terra L, Heemskerk-Gerritsen B, van der Aalst C, Roeters van Lennep J, van Beurden M, et al.
JACC CardioOncol . 2025 Jan; 6(6):922-931. PMID: 39801648
Background: Premenopausal risk-reducing salpingo-oophorectomy (RRSO) in women at high familial risk of ovarian cancer leads to immediate menopause. Although early natural menopause is associated with increased cardiovascular disease risk, evidence...
4.
Stroot I, Bart J, Hollema H, Wagner M, Yigit R, van Doorn H, et al.
J Natl Cancer Inst . 2024 Nov; PMID: 39579093
Background: Risk-reducing salpingo-oophorectomy (RRSO) effectively prevents high-grade serous carcinoma (HGSC) in BRCA1/2 germline pathogenic variant (GPV) carriers. Still, some women develop HGSC after RRSO without pathologic findings. This study assessed...
5.
Bogaerts J, Steenbeek M, Bokhorst J, van Bommel M, Abete L, Addante F, et al.
J Pathol Clin Res . 2024 Oct; 10(6):e70006. PMID: 39439213
In recent years, it has become clear that artificial intelligence (AI) models can achieve high accuracy in specific pathology-related tasks. An example is our deep-learning model, designed to automatically detect...
6.
Negri S, Fisch C, de Hullu J, van Bommel M, Simons M, Bogaerts J, et al.
BJOG . 2024 Jul; 131(13):1851-1861. PMID: 39054407
Objective: A Serous Tubal Intraepithelial Carcinoma (STIC) without concomitant invasive carcinoma is occasionally identified and associated with a high risk of subsequent peritoneal carcinomatosis. Management needs optimisation. This study explores...
7.
Kwinten K, Lemain V, de Hullu J, Leenders W, Steenbeek M, Van Altena A, et al.
Cancer Med . 2024 Jul; 13(14):e70000. PMID: 39031958
Background: In the last decade, technical innovations have resulted in the development of several minimally invasive diagnostic cancer tools. Within women at high risk of developing ovarian or endometrial cancer...
8.
Witjes V, Hermkens D, Swillens J, Smolders Y, Mourits M, Ausems M, et al.
Fam Cancer . 2024 May; 23(4):429-436. PMID: 38811422
Genetic testing in patients with ovarian carcinoma (OC) is crucial, as around 10-15% of these women have a genetic predisposition to OC. Although guidelines have recommended universal germline testing for...
9.
Stroot I, Bart J, Hollema H, Jalving M, Wagner M, Yigit R, et al.
Gynecol Oncol . 2024 May; 187:198-203. PMID: 38795508
Objective: The aim of this study was to describe the long-term outcome of asymptomatic BRCA1/2 germline pathogenic variant (GPV) carriers with high-grade serous carcinoma (HGSC) in their risk-reducing salpingo-oophorectomy (RRSO)...
10.
Said S, IntHout J, den Ouden J, Walraven J, van der Aa M, de Hullu J, et al.
J Clin Med . 2024 May; 13(10). PMID: 38792332
To assess the association between pretreatment thrombocytosis, anemia, and leukocytosis and overall survival (OS) of advanced-stage EOC. Furthermore, to develop nomograms using established prognostic factors and pretreatment hematologic parameters to...