Joanna Czarnecka-Herok
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Explore the profile of Joanna Czarnecka-Herok including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
158
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0
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Recent Articles
1.
Czarnecka-Herok J, Zhu K, Flaman J, Goehrig D, Vernier M, Makulyte G, et al.
Redox Biol
. 2024 May;
73:103204.
PMID: 38810421
The ELN gene encodes tropoelastin which is used to generate elastic fibers that insure proper tissue elasticity. Decreased amounts of elastic fibers and/or accumulation of bioactive products of their cleavage,...
2.
Ziegler D, Czarnecka-Herok J, Vernier M, Scholtes C, Camprubi C, Huna A, et al.
NPJ Aging
. 2024 Jan;
10(1):5.
PMID: 38216569
Cellular senescence is a cell program induced by various stresses that leads to a stable proliferation arrest and to a senescence-associated secretory phenotype. Accumulation of senescent cells during age-related diseases...
3.
Martin N, Zhu K, Czarnecka-Herok J, Vernier M, Bernard D
Cell Calcium
. 2023 Feb;
110:102701.
PMID: 36736165
Cellular senescence is a state of stable cell proliferation arrest accompanied by a distinct secretory program impacting the senescent cell microenvironment. This phenotype can be induced by many stresses, including...
4.
Czarnecka-Herok J, Sliwinska M, Herok M, Targonska A, Strzeszewska-Potyrala A, Bojko A, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955416
Upon anticancer treatment, cancer cells can undergo cellular senescence, i.e., the temporal arrest of cell division, accompanied by polyploidization and subsequent amitotic divisions, giving rise to mitotically dividing progeny. In...
5.
Strzeszewska-Potyrala A, Staniak K, Czarnecka-Herok J, Rafiee M, Herok M, Mosieniak G, et al.
Cancers (Basel)
. 2021 Apr;
13(9).
PMID: 33925586
The p21 protein, encoded by , plays a vital role in senescence, and its transcriptional control by the tumour suppressor p53 is well-established. However, p21 can also be regulated in...
6.
Sikora E, Czarnecka-Herok J, Bojko A, Sunderland P
Semin Cancer Biol
. 2020 Dec;
81:83-95.
PMID: 33271316
Polyploid somatic cells have 'programmed' roles in normal development and stress responses. Transient polyploidy states have been observed in several tumor types at early stages of tumorigenesis. They can give...
7.
Bojko A, Staniak K, Czarnecka-Herok J, Sunderland P, Dudkowska M, Sliwinska M, et al.
Int J Mol Sci
. 2020 Aug;
21(17).
PMID: 32846959
The induction of senescence/polyploidization and their role in cancer recurrence is still a poorly explored issue. We showed that MDA-MB-231 and MCF-7 breast cancer cells underwent reversible senescence/polyploidization upon pulse...
8.
Juraszek B, Czarnecka-Herok J, Nalecz K
J Neurochem
. 2020 Jul;
156(5):642-657.
PMID: 32654140
Gliomas are the most common primary malignant brain tumor in adults, but current treatment for glioblastoma multiforme (GBM) is insufficient. Even though glucose is the primary energetic substrate of glioma...
9.
Bojko A, Czarnecka-Herok J, Charzynska A, Dabrowski M, Sikora E
Cells
. 2019 Nov;
8(12).
PMID: 31771226
It is acknowledged that cancer cells are able to undergo senescence in response to clinically used chemotherapeutics. Moreover, recent years have provided evidence that some drugs can selectively remove senescent...