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JoAnn D Coleman-McCray

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Recent Articles
1.
Welch S, Spengler J, Westover J, Bailey K, Davies K, Aida-Ficken V, et al.
Sci Transl Med . 2024 Nov; 16(774):eado7034. PMID: 39565871
Development of broad-spectrum antiviral therapies is critical for outbreak and pandemic preparedness against emerging and reemerging viruses. Viruses inducing hemorrhagic fevers cause high morbidity and mortality in humans and are...
2.
Sorvillo T, Ritter J, Welch S, Coleman-McCray J, Davies K, Hayes H, et al.
Emerg Microbes Infect . 2024 Nov; 13(1):2427782. PMID: 39513496
Crimean-Congo haemorrhagic fever virus (CCHFV) causes human disease ranging from subclinical to a fatal haemorrhagic syndrome. Determinants of CCHF pathogenesis are largely unknown and animal models that recapitulate human disease...
3.
Lo M, Jain S, Davies K, Sorvillo T, Welch S, Coleman-McCray J, et al.
Antiviral Res . 2024 Sep; 231:106013. PMID: 39326503
Nipah virus (NiV) causes near-annual outbreaks of fatal encephalitis and respiratory disease in South Asia with a high mortality rate (∼70%). Since there are no approved therapeutics for NiV disease...
4.
Karaaslan E, Sorvillo T, Scholte F, ONeal T, Welch S, Davies K, et al.
NPJ Vaccines . 2024 Aug; 9(1):148. PMID: 39143104
Immunizing mice with Crimean-Congo hemorrhagic fever virus (CCHFV) nucleoprotein (NP), glycoprotein precursor (GPC), or with the GP38 domain of GPC, can be protective when the proteins are delivered with viral...
5.
Sorvillo T, Karaaslan E, Scholte F, Welch S, Coleman-McCray J, Genzer S, et al.
NPJ Vaccines . 2024 May; 9(1):88. PMID: 38782933
Crimean-Congo hemorrhagic fever virus (CCHFV) can cause severe human disease and is considered a WHO priority pathogen due to the lack of efficacious vaccines and antivirals. A CCHF virus replicon...
6.
Scholte F, Spengler J, Welch S, Harmon J, Coleman-McCray J, Davies K, et al.
Virus Res . 2024 May; 345:199398. PMID: 38754786
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne nairovirus with a wide geographic spread that can cause severe and lethal disease. No specific medical countermeasures are approved to combat this...
7.
Wier R, Flietstra T, Coleman-McCray J, Genzer S, Brake M, Velazquez E, et al.
J Am Assoc Lab Anim Sci . 2024 Apr; 63(4):385-396. PMID: 38580436
Type of feed is an important consideration in herbivore colony management, yet limited studies report on the effects of diet on common conditions such as urolithiasis in guinea pigs. Urolithiasis...
8.
Guito J, Arnold C, Schuh A, Amman B, Sealy T, Spengler J, et al.
Front Immunol . 2024 Jan; 14:1306501. PMID: 38259437
Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, ), the only known MARV reservoir, shows no overt...
9.
Scholte F, Rodriguez S, Welch S, Davies K, Genzer S, Coleman-McCray J, et al.
J Infect Dis . 2023 Dec; 230(2):438-443. PMID: 38064677
Nipah virus (NiV) is a highly pathogenic paramyxovirus. The Syrian hamster model recapitulates key features of human NiV disease and is a critical tool for evaluating antivirals and vaccines. Here...
10.
Davies K, Welch S, Sorvillo T, Coleman-McCray J, Martin M, Brignone J, et al.
Sci Rep . 2023 Nov; 13(1):19384. PMID: 37938597
Reverse-transcription quantitative polymerase chain reaction assays are frequently used to evaluate gene expression in animal model studies. Data analyses depend on normalization using a suitable reference gene (RG) to minimize...