Joana A Vidigal
Overview
Explore the profile of Joana A Vidigal including associated specialties, affiliations and a list of published articles.
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20
Citations
1151
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Recent Articles
1.
Prajapat M, Maria A, Vidigal J
Nucleic Acids Res
. 2024 Dec;
53(1.
PMID: 39673524
Non-coding regulatory sequences play essential roles in adjusting gene output to cellular needs and are thus critical to animal development and health. Numerous such sequences have been identified in mammalian...
2.
Prajapat M, Vidigal J
bioRxiv
. 2024 Sep;
PMID: 39282279
Non-coding regulatory sequences play essential roles in adjusting gene output to cellular needs and are thus critical to animal development and health. Numerous such sequences have been identified in mammalian...
3.
Prajapat M, Sala L, Vidigal J
RNA
. 2024 Aug;
30(11):1465-1476.
PMID: 39209555
Vault RNAs (vtRNAs) are evolutionarily conserved small noncoding RNAs transcribed by RNA polymerase III. Vault RNAs were initially described as components of the vault particle, but have since been assigned...
4.
Xiao M, Damodaran A, Kumari B, Dickson E, Xing K, On T, et al.
Mol Cell
. 2024 Jun;
84(13):2553-2572.e19.
PMID: 38917794
CRISPR-Cas technology has transformed functional genomics, yet understanding of how individual exons differentially shape cellular phenotypes remains limited. Here, we optimized and conducted massively parallel exon deletion and splice-site mutation...
5.
Prajapat M, Sala L, Vidigal J
bioRxiv
. 2024 Jun;
PMID: 38895289
Vault RNAs (vRNAs) are evolutionarily conserved small non-coding RNAs transcribed by RNA polymerase lll. Initially described as components of the vault particle, they have since also been described as noncanonical...
6.
7.
Sala L, Kumar M, Prajapat M, Chandrasekhar S, Cosby R, La Rocca G, et al.
Nat Struct Mol Biol
. 2023 Nov;
30(12):1985-1995.
PMID: 37985687
Argonaute 2 (AGO2) is a cytoplasmic component of the miRNA pathway, with essential roles in development and disease. Yet little is known about its regulation in vivo. Here we show...
8.
Perez A, Sala L, Perez R, Vidigal J
Nat Commun
. 2022 Apr;
13(1):1893.
PMID: 35365673
No abstract available.
9.
Perez A, Sala L, Perez R, Vidigal J
Nat Commun
. 2021 Nov;
12(1):6461.
PMID: 34753924
Off-target effects are well established confounders of CRISPR negative selection screens that impair the identification of essential genomic loci. In particular, non-coding regulatory elements and repetitive regions are often difficult...
10.
Sala L, Chandrasekhar S, Vidigal J
Front Biosci (Landmark Ed)
. 2019 Oct;
25(1):1-42.
PMID: 31585876
Argonaute (AGO) proteins play key roles in animal physiology by binding to small RNAs and regulating the expression of their targets. In mammals, they do so through two distinct pathways:...