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Joan L Buss

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Articles 14
Citations 324
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Recent Articles
1.
OConaill C, Malisza K, Buss J, Bolster R, Clancy C, de Gervai P, et al.
J Neurodev Disord . 2015 Mar; 7(1):10. PMID: 25750685
Background: Alcohol-related neurodevelopmental disorder (ARND) falls under the umbrella of fetal alcohol spectrum disorder (FASD). Diagnosis of ARND is difficult because individuals do not demonstrate the characteristic facial features associated...
2.
Malisza K, Buss J, Bolster R, de Gervai P, Woods-Frohlich L, Summers R, et al.
J Neurodev Disord . 2012 Sep; 4(1):12. PMID: 22958510
Background: Alcohol related neurodevelopmental disorder (ARND) falls under the umbrella of fetal alcohol spectrum disorder (FASD), but individuals do not demonstrate the facial characteristics associated with fetal alcohol syndrome (FAS),...
3.
Szuber N, Buss J, Soe-Lin S, Felfly H, Trudel M, Ponka P
Exp Hematol . 2008 May; 36(7):773-85. PMID: 18456387
Objective: beta-thalassemia major, or Cooley's anemia, is a red blood cell disorder requiring lifelong blood transfusions for survival. Erythrocytes accumulate toxic iron at their membranes, triggering an oxidative cascade that...
4.
Jiao Y, Wilkinson 4th J, Pietsch E, Buss J, Wang W, Planalp R, et al.
Free Radic Biol Med . 2006 Mar; 40(7):1152-60. PMID: 16545682
Curcumin is among the more successful chemopreventive compounds investigated in recent years, and is currently in human trials to prevent cancer. The mechanism of action of curcumin is complex and...
5.
Wilkinson 4th J, Di X, Schonig K, Buss J, Kock N, Cline J, et al.
Biochem J . 2006 Feb; 395(3):501-7. PMID: 16448386
Ferritin is a ubiquitously distributed iron-binding protein. Cell culture studies have demonstrated that ferritin plays a role in maintenance of iron homoeostasis and in the protection against cytokine- and oxidant-induced...
6.
Buss J, Greene B, Turner J, Torti F, Torti S
Curr Top Med Chem . 2004 Dec; 4(15):1623-35. PMID: 15579100
Iron chelators may be of value as therapeutic agents in the treatment of cancer. They may act by depleting iron, a necessary nutrient, and limiting tumor growth. Alternatively or additionally,...
7.
Buss J, Neuzil J, Ponka P
Arch Biochem Biophys . 2003 Dec; 421(1):1-9. PMID: 14678779
Pyridoxal isonicotinoyl hydrazone (PIH) and many of its analogs are effective iron chelators in vivo and in vitro, and are of interest for the treatment of secondary iron overload. Because...
8.
Buss J, Torti F, Torti S
Curr Med Chem . 2003 Apr; 10(12):1021-34. PMID: 12678674
This review focuses on advances and strategies in the use of iron chelators as anti-tumor therapies. Although the development of iron chelators for human disease has focused primarily on their...
9.
Buss J, Hermes-Lima M, Ponka P
Adv Exp Med Biol . 2003 Feb; 509:205-29. PMID: 12572996
No abstract available.
10.
Buss J, Arduini E, Shephard K, Ponka P
Biochem Pharmacol . 2003 Jan; 65(3):349-60. PMID: 12527328
Iron overload secondary to beta-thalassemia and other iron-loading anemias is the most serious obstacle to be overcome in the treatment of these diseases, since there is no physiological mechanism for...