Joachim Riethmuller
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Explore the profile of Joachim Riethmuller including associated specialties, affiliations and a list of published articles.
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31
Citations
1092
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Recent Articles
1.
Bernhard W, Lange R, Graepler-Mainka U, Engel C, Machann J, Hund V, et al.
Nutrients
. 2019 Mar;
11(3).
PMID: 30889905
Background: Choline is essential for the synthesis of liver phosphatidylcholine (PC), parenchymal maintenance, bile formation, and lipoprotein assembly to secrete triglycerides. In choline deficiency, the liver accretes choline/PC at the...
2.
Haque A, Dewerth A, Antony J, Riethmuller J, Schweizer G, Weinmann P, et al.
Sci Rep
. 2018 Nov;
8(1):16776.
PMID: 30425265
Gene therapy has always been a promising therapeutic approach for Cystic Fibrosis (CF). However, numerous trials using DNA or viral vectors encoding the correct protein resulted in a general low...
3.
Rath D, Chatterjee M, Meyer L, Tekath N, Olma C, Krumm P, et al.
Atherosclerosis
. 2018 Oct;
278:269-277.
PMID: 30342381
Background And Aims: Platelets are critically involved in tissue repair and regeneration, which depend on their inflammatory properties and survival. SDF-1 ligates to CXCR4 and CXCR7 and contributes to the...
4.
Becker K, Riethmuller J, Seitz A, Gardner A, Boudreau R, Kamler M, et al.
Adv Drug Deliv Rev
. 2018 Apr;
133:66-75.
PMID: 29698625
Studies over the past several years have demonstrated the important role of sphingolipids in cystic fibrosis (CF), chronic obstructive pulmonary disease and acute lung injury. Ceramide is increased in airway...
5.
Keitsch S, Riethmuller J, Soddemann M, Sehl C, Wilker B, Edwards M, et al.
Biol Chem
. 2018 Apr;
399(10):1203-1213.
PMID: 29613852
Pulmonary infections of cystic fibrosis (CF) patients with Staphylococcus aureus (S. aureus) occur very early in the disease. The molecular details that cause infection-susceptibility of CF patients to and mediate...
6.
Hartleif S, Schumm M, Doring M, Mezger M, Lang P, Dahlke M, et al.
Stem Cells Int
. 2017 Jul;
2017:2352954.
PMID: 28740511
Background: Calcineurin inhibitors (CNI) have significantly improved patient and graft survival in pediatric liver transplantation (pLT). However, CNI toxicity leads to significant morbidity. Moreover, CNIs cannot prevent long-term allograft injury....
7.
Grassme H, Henry B, Ziobro R, Becker K, Riethmuller J, Gardner A, et al.
Cell Host Microbe
. 2017 May;
21(6):707-718.e8.
PMID: 28552668
Chronic pulmonary colonization with bacterial pathogens, particularly Pseudomonas aeruginosa, is the primary cause of morbidity and mortality in patients with cystic fibrosis (CF). We observed that β1-integrins accumulate on the...
8.
Junge S, Gorlich D, den Reijer M, Wiedemann B, Tummler B, Ellemunter H, et al.
PLoS One
. 2016 Nov;
11(11):e0166220.
PMID: 27861524
Background: Staphylococcus aureus is an important pathogen in cystic fibrosis (CF). However, it is not clear which factors are associated with worse lung function in patients with persistent S. aureus...
9.
Riethmuller J, Herrmann G, Graepler-Mainka U, Hellwig D, Heuer H, Heyder S, et al.
Cell Physiol Biochem
. 2016 Sep;
39(3):1141-51.
PMID: 27576543
Background/aims: In cystic fibrosis (CF), chronic microbial lung infections are difficult to treat and cause morbidity and increased mortality. Methods: In a multicentre, open-label, exploratory, non-interventional study, inhaled tobramycin (300...
10.
Mainz J, Schumacher U, Schadlich K, Hentschel J, Koitschev C, Koitschev A, et al.
J Cyst Fibros
. 2016 Jun;
15(6):e57-e66.
PMID: 27267518
Background: Chronic rhinosinusitis is a hallmark of Cystic fibrosis (CF) impairing the patients' quality of life and overall health. However, therapeutic options have not been sufficiently evaluated. Bronchial inhalation of...