Joachim Hoppmann
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Explore the profile of Joachim Hoppmann including associated specialties, affiliations and a list of published articles.
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4
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66
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Recent Articles
1.
Baumer W, Hoppmann J, Rundfeldt C, Kietzmann M
Inflamm Allergy Drug Targets
. 2007 Mar;
6(1):17-26.
PMID: 17352685
The phosphodiesterase (PDE) 4 is the predominant cyclic AMP degrading enzyme in a variety of inflammatory cells including eosinophils, neutrophils, macrophages, T cells and monocytes. In addition, this enzyme is...
2.
Hoppmann J, Baumer W, Galetzka C, Hofgen N, Kietzmann M, Rundfeldt C
J Pharm Pharmacol
. 2005 Dec;
57(12):1609-17.
PMID: 16354405
The selective phosphodiesterase 4 (PDE4) inhibitor AWD 12-281 is structurally optimized for topical administration. It has potent effects in models of lung inflammation if administered as a dry powder inhalation....
3.
Baumer W, Gorr G, Hoppmann J, Ehinger A, Rundfeldt C, Kietzmann M
J Pharm Pharmacol
. 2003 Sep;
55(8):1107-14.
PMID: 12956900
AWD 12-281 (N-(3,5-dichloro-4-pyridinyl)-2-[1-(4-fluorobenzyl)-5-hydroxy-1H-indol-3-yl]-2-oxoacetamide), a phosphodiesterase 4 inhibitor, which is optimized for topical administration, was tested in a model of allergic dermatitis in mice. To obtain an allergic dermatitis, BALB/c mice...
4.
Baumer W, Gorr G, Hoppmann J, Ehinger A, Ehinger B, Kietzmann M
Eur J Pharmacol
. 2002 Jul;
446(1-3):195-200.
PMID: 12098602
The inhibitors of the phosphodiesterase 4, SB 207499 (cilomilast, c-4-cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)-r-L-cyclohexane carboxylic acid) and AWD 12-281 (N-(3,5-dichloropyrid-4-yl)-[1-(4-fluorobenzyl)-5-hydroxy-indole-3-yl]-glyoxylic acid amide) were tested in a model of allergic dermatitis in mice. To obtain...