Chris Rundfeldt
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Explore the profile of Chris Rundfeldt including associated specialties, affiliations and a list of published articles.
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31
Citations
292
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Recent Articles
1.
Hameed M, DAmbrosio R, Eastman C, Hui B, Lin R, Vermudez S, et al.
Exp Neurol
. 2024 Sep;
382:114962.
PMID: 39288831
Post-traumatic epilepsy (PTE) is a recurrent and often drug-refractory seizure disorder caused by traumatic brain injury (TBI). No single drug treatment prevents PTE, but preventive drug combinations that may prophylax...
2.
Rundfeldt C, Klein P, Boison D, Rotenberg A, DAmbrosio R, Eastman C, et al.
Epilepsia
. 2023 Jan;
64(4):888-899.
PMID: 36708090
Objective: For an antiseizure medication (ASM) to be effective in status epilepticus (SE), the drug should be administered intravenously (i.v.) to provide quick access to the brain. However, poor aqueous...
3.
Engel O, Masic A, Landsberg G, Brooks M, Mills D, Rundfeldt C
Front Pharmacol
. 2018 Nov;
9:1225.
PMID: 30455643
Imepitoin is a low affinity partial agonist for the benzodiazepine binding site of γ-aminobutyric acid (GABA) receptors, and is currently used as an antiepileptic in dogs. Here we tested imepitoin...
4.
Nessler J, Rundfeldt C, Loscher W, Kostic D, Keefe T, Tipold A
BMC Vet Res
. 2017 Jan;
13(1):33.
PMID: 28118828
Background: Imepitoin was tested as a combination treatment with phenobarbital in an open-label mono-centre cohort study in dogs with drug-resistant epilepsy. Diagnosis of idiopathic epilepsy was based on clinical findings,...
5.
6.
Rundfeldt C, Tipold A, Loscher W
BMC Vet Res
. 2015 Sep;
11:228.
PMID: 26330063
Background: Imepitoin is a novel antiepileptic drug for the treatment of canine idiopathic epilepsy. The present study was conducted to demonstrate superior antiepileptic activity of a high dose of 30...
7.
Job F, Settele F, Lorey S, Rundfeldt C, Baumann L, Beck-Sickinger A, et al.
FEBS Open Bio
. 2015 Aug;
5:579-93.
PMID: 26258013
In the search for effective therapeutic strategies, protein-based biologicals are under intense development. While monoclonal antibodies represent the majority of these drugs, other innovative approaches are exploring the use of...
8.
Walliser U, Fenner A, Mohren N, Keefe T, deVries F, Rundfeldt C
BMC Vet Res
. 2015 May;
11:113.
PMID: 25976845
Background: The benefit of pre and post-operative administration of non-steroidal anti-inflammatory drugs for the relief of post-operative pain and control of inflammation in horses following orthopaedic surgery has not been...
9.
Wlaz P, Knaga S, Kasperek K, Wlaz A, Poleszak E, Jezewska-Witkowska G, et al.
Mycopathologia
. 2015 Mar;
180(1-2):35-42.
PMID: 25790942
Pulmonary aspergillosis is frequently reported in parrots, falcons, and other birds held in captivity. Inhalation is the main route of infection for Aspergillus fumigatus, resulting in both acute and chronic...
10.
Wlaz P, Poleszak E, Serefko A, Wlaz A, Rundfeldt C
Pharmacol Rep
. 2015 Feb;
67(2):349-52.
PMID: 25712662
Background: Anxiety and depression affect epileptic patients much more often than individuals from the general population. We were interested in whether corneal kindling in rats, which is a model of...