Jo Rae Wright
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Explore the profile of Jo Rae Wright including associated specialties, affiliations and a list of published articles.
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63
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2178
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Recent Articles
11.
Wang Y, Zhu Z, Church T, Lugogo N, Que L, Francisco D, et al.
J Immunol
. 2012 Feb;
188(7):3371-81.
PMID: 22371396
Asthma is a chronic inflammatory disease in which airway epithelial cells are the first line of defense against exposure of the airway to infectious agents. Src homology protein (SHP)-1, a...
12.
Mukherjee S, Giamberardino C, Thomas J, Evans K, Goto H, Ledford J, et al.
J Immunol
. 2012 Jan;
188(3):957-67.
PMID: 22219327
Pulmonary surfactant lipoproteins lower the surface tension at the alveolar-airway interface of the lung and participate in host defense. Previous studies reported that surfactant protein A (SP-A) inhibits lymphocyte proliferation....
13.
Aono Y, Ledford J, Mukherjee S, Ogawa H, Nishioka Y, Sone S, et al.
Am J Respir Crit Care Med
. 2011 Dec;
185(5):525-36.
PMID: 22198976
Rationale: Surfactant protein (SP)-D and SP-A have been implicated in immunomodulation in the lung. It has been reported that patients with idiopathic pulmonary fibrosis (IPF) often have elevated serum levels...
14.
Wang Y, Voelker D, Lugogo N, Wang G, Floros J, Ingram J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2011 Jul;
301(4):L598-606.
PMID: 21784968
Surfactant protein A (SP-A) regulates a variety of immune cell functions. We determined the ability of SP-A derived from normal and asthmatic subjects to modulate the inflammatory response elicited by...
15.
Snegovskikh V, Bhandari V, Wright J, Tadesse S, Morgan T, MacNeill C, et al.
J Clin Endocrinol Metab
. 2011 Jan;
96(4):E624-32.
PMID: 21270323
Context: Labor is characterized by "decidual activation" with production of inflammatory mediators. Recent data suggest that surfactant protein-A (SP-A) may be critical to the onset of labor in mice. Whether...
16.
Pastva A, Mukherjee S, Giamberardino C, Hsia B, Lo B, Sempowski G, et al.
J Immunol
. 2011 Jan;
186(5):2842-9.
PMID: 21257967
Although many studies have shown that pulmonary surfactant protein (SP)-A functions in innate immunity, fewer studies have addressed its role in adaptive immunity and allergic hypersensitivity. We hypothesized that SP-A...
17.
Ledford J, Lo B, Kislan M, Thomas J, Evans K, Cain D, et al.
J Immunol
. 2010 Sep;
185(7):3884-94.
PMID: 20810986
During pulmonary infections, a careful balance between activation of protective host defense mechanisms and potentially injurious inflammatory processes must be maintained. Surfactant protein A (SP-A) is an immune modulator that...
18.
Ledford J, Pastva A, Wright J
Innate Immun
. 2010 Apr;
16(3):183-90.
PMID: 20418258
Although the lipoprotein complex of pulmonary surfactant has long been recognized as essential for reducing lung surface tension, its role in lung immune host defense has only relatively recently been...
19.
Pastva A, Walker J, Maddox L, Mukherjee S, Giamberardino C, Hsia B, et al.
Am J Respir Cell Mol Biol
. 2010 Mar;
44(2):175-84.
PMID: 20348208
Surfactant protein A (SP-A) mediates innate immune cell responses to LPS, a cell wall component of gram-negative bacteria that is found ubiquitously in the environment and is associated with adverse...
20.
Zaas D, Swan Z, Brown B, Wright J, Abraham S
Commun Integr Biol
. 2010 Mar;
2(6):535-7.
PMID: 20195460
Caveolin proteins have been implicated in a wide range of cellular functions including lipid raft mediated endocytosis and regulation of cell signaling cascades. Recent discoveries have shown that these proteins...