Jisha Antony
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Explore the profile of Jisha Antony including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
245
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Recent Articles
1.
Gimenez G, Kalev-Zylinska M, Morison I, Bohlander S, Horsfield J, Antony J
Am J Physiol Cell Physiol
. 2024 Nov;
328(1):C9-C19.
PMID: 39548947
Cohesin complex is essential for cell division and regulating cell type-specific gene expression programs. Mutations in genes encoding the cohesin subunits are associated with hematological malignancies, preleukemia, and clonal hematopoiesis...
2.
Labudina A, Meier M, Gimenez G, Tatarakis D, Ketharnathan S, Mackie B, et al.
Development
. 2024 Jul;
151(15).
PMID: 38975838
Cohesin, a chromatin-associated protein complex with four core subunits (Smc1a, Smc3, Rad21 and either Stag1 or 2), has a central role in cell proliferation and gene expression in metazoans. Human...
3.
Banerjee R, Ajithkumar P, Keestra N, Smith J, Gimenez G, Rodger E, et al.
Cancers (Basel)
. 2024 Mar;
16(5).
PMID: 38473261
Cutaneous melanoma is rapidly on the rise globally, surpassing the growth rate of other cancers, with metastasis being the primary cause of death in melanoma patients. Consequently, understanding the mechanisms...
4.
Thomas A, Marsman J, Antony J, Schierding W, OSullivan J, Horsfield J
Genes (Basel)
. 2021 Aug;
12(8).
PMID: 34440349
The gene encodes a developmental transcription factor that is an important regulator of haematopoiesis in vertebrates. Genetic disruptions to the gene are frequently associated with acute myeloid leukaemia. Gene regulatory...
5.
Antony J, Chin C, Horsfield J
Int J Mol Sci
. 2021 Jul;
22(13).
PMID: 34202641
The cohesin complex is crucial for mediating sister chromatid cohesion and for hierarchal three-dimensional organization of the genome. Mutations in cohesin genes are present in a range of cancers. Extensive...
6.
Chin C, Antony J, Ketharnathan S, Labudina A, Gimenez G, Parsons K, et al.
Elife
. 2020 Dec;
9.
PMID: 33284104
Mutations in genes encoding subunits of the cohesin complex are common in several cancers, but may also expose druggable vulnerabilities. We generated isogenic MCF10A cell lines with deletion mutations of...
7.
Antony J, Gimenez G, Taylor T, Khatoon U, Day R, Morison I, et al.
J Mol Cell Biol
. 2020 Jan;
12(5):397-399.
PMID: 31897485
No abstract available.
8.
Leask M, Dowdle A, Salvesen H, Topless R, Fadason T, Wei W, et al.
Front Genet
. 2019 May;
10:382.
PMID: 31105747
[This corrects the article DOI: 10.3389/fgene.2018.00733.].
9.
Leask M, Dowdle A, Salvesen H, Topless R, Fadason T, Wei W, et al.
Front Genet
. 2019 Feb;
9:733.
PMID: 30719032
Genetic variation in the genomic regulatory landscape likely plays a crucial role in the pathology of disease. Non-coding variants associated with disease can influence the expression of long intergenic non-coding...
10.
Ketharnathan S, Leask M, Boocock J, Phipps-Green A, Antony J, OSullivan J, et al.
Hum Mol Genet
. 2018 Aug;
27(22):3964-3973.
PMID: 30124855
The precise molecular mechanisms by which urate-associated genetic variants affect urate levels are unknown. Here, we tested for functional linkage of the maximally associated genetic variant rs1967017 at the PDZK1...