Jiqin Wu
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Explore the profile of Jiqin Wu including associated specialties, affiliations and a list of published articles.
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18
Citations
457
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Recent Articles
1.
Ai J, Wang H, Zhang H, Song J, Zhang Y, Lin K, et al.
Heliyon
. 2024 Jul;
10(12):e32304.
PMID: 38948033
Background: Several respiratory infections outbreaks have been observed in mainland China after reduction of non-pharmaceutical interventions. Other countries have seen increases in respiratory infections outside typical seasons post-COVID-19, warranting investigation...
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Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, et al.
Nat Commun
. 2024 May;
15(1):4620.
PMID: 38816392
Influenza viruses and thogotoviruses account for most recognized orthomyxoviruses. Thogotoviruses, exemplified by Thogoto virus (THOV), are capable of infecting humans using ticks as vectors. THOV transcribes mRNA without the extraneous...
4.
Wang X, Jing X, Shi J, Liu Q, Shen S, Cheung P, et al.
Nucleic Acids Res
. 2024 Jan;
52(6):3278-3290.
PMID: 38296832
Jingmenviruses are a category of emerging segmented viruses that have garnered global attention in recent years, and are close relatives of the flaviviruses in the Flaviviridae family. One of their...
5.
Tan Z, Wu J, Huang L, Wang T, Zheng Z, Zhang J, et al.
PLoS Pathog
. 2023 Sep;
19(9):e1011620.
PMID: 37656756
LGP2 is a RIG-I-like receptor (RLR) known to bind and recognize the intermediate double-stranded RNA (dsRNA) during virus infection and to induce type-I interferon (IFN)-related antiviral innate immune responses. Here,...
6.
Wu J, Zheng H, Gong P
J Biol Chem
. 2023 May;
299(7):104872.
PMID: 37257822
African swine fever virus (ASFV) is an important animal pathogen that is causing a current African swine fever pandemic and affecting pork industry globally. ASFV encodes at least 150 proteins,...
7.
Wu J, Wang X, Liu Q, Lu G, Gong P
Proc Natl Acad Sci U S A
. 2022 Dec;
120(1):e2211425120.
PMID: 36577062
De novo viral RNA-dependent RNA polymerases (RdRPs) utilize their priming element (PE) to facilitate accurate initiation. Upon transition to elongation, the PE has to retreat from the active site to...
8.
Chen S, Wu J, Yang X, Sun Q, Liu S, Rashid F, et al.
Microbiol Spectr
. 2022 Aug;
10(5):e0272922.
PMID: 35980196
The virus-encoded RNA-dependent RNA polymerase (RdRp) is responsible for viral replication, and its fidelity is closely related to viral diversity, pathogenesis, virulence, and fitness. Hepatitis C virus (HCV) and the...
9.
Liu Q, Wu J, Gong P
STAR Protoc
. 2022 Jun;
3(3):101468.
PMID: 35761985
Nucleotide/nucleoside analogs (NAs) are important compounds used in antiviral drug development. To understand the action mode of NA drugs, we present an enzymology protocol to initially evaluate the intervention mechanism...
10.
Wu J, Wang H, Liu Q, Li R, Gao Y, Fang X, et al.
Cell Rep
. 2021 Oct;
37(4):109882.
PMID: 34653416
Remdesivir (RDV), a nucleotide analog with broad-spectrum features, has exhibited effectiveness in COVID-19 treatment. However, the precise working mechanism of RDV when targeting the viral RNA-dependent RNA polymerase (RdRP) has...