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Jinjun Chen

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Articles 141
Citations 1181
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Recent Articles
1.
Zhou H, Li H, Deng G, Wang X, Zheng X, Chen J, et al.
QJM . 2025 Feb; PMID: 39977385
Background And Aims: To establish an early and quick model for diagnosing infections in patients with acute-on-chronic liver disease (AoCLD). Approach: This study analyzed 3,949 patients from two multicenter prospective...
2.
Song Y, Ni W, Zheng M, Sheng H, Wang J, Xie S, et al.
Cell Rep Med . 2025 Feb; 6(2):101939. PMID: 39970876
The efficacy and safety of a lower dose of vitamin E for metabolic dysfunction-associated steatohepatitis (MASH) treatment are unclear. This multi-center, randomized, double-blind, placebo-controlled study includes 124 non-diabetic participants with...
3.
Yu X, Zhou R, Tan W, Wang X, Zheng X, Huang Y, et al.
eGastroenterology . 2025 Feb; 2(3):e100101. PMID: 39944361
Background: The model for end-stage liver disease (MELD) score is widely used for the prognostication in end-stage liver disease but has limited performance in acute-on-chronic liver failure (ACLF). In this...
4.
Wang H, Liang W, Zhou L, Song J, Wen B, Wu Q, et al.
Clin Mol Hepatol . 2025 Feb; PMID: 39905841
Background & Aims: Cirrhotic patients with liver stiffness measurement (LSM) <20kPa and platelet count ≥150/ul (Baveno VI criteria), otherwise spleen stiffness measurement (SSM) ≤ 40kPa (Baveno VI-SSM criteria) can avoid...
5.
Lan X, Hong C, Zhang X, Zhou L, Li Y, Zhang C, et al.
J Gastroenterol Hepatol . 2025 Jan; PMID: 39871448
Background & Aims: Acute-on-chronic liver failure (ACLF) is a complex syndrome with limited treatment options. This study aims to investigate the impact of artificial liver support system (ALSS) on the...
6.
He X, Hu M, Xu Y, Xia F, Tan Y, Wang Y, et al.
Nat Med . 2025 Jan; 31(2):627-638. PMID: 39779925
Up to 50-70% of patients with liver cirrhosis develop hepatic encephalopathy (HE), which is closely related to gut microbiota dysbiosis, with an unclear mechanism. Here, by constructing gut-brain modules to...
7.
Chen J, Gu Z, Perez-Aguilar J, Luo Y, Tian K, Luo Y
Sci Rep . 2025 Jan; 15(1):199. PMID: 39748078
Two-dimensional (2D) metal-organic frameworks (MOFs) have been extensively utilized across various research areas. However, the application of 2D MOF-based membranes for the removal of heavy metal ions remains largely unexplored,...
8.
Ding J, Liu H, Zhang X, Zhao N, Peng Y, Shi J, et al.
Sci Transl Med . 2024 Nov; 16(772):eadh9940. PMID: 39504356
Nonalcoholic fatty liver disease (NAFLD) has become a common health care burden worldwide. The high heterogeneity of NAFLD remains elusive and impairs outcomes of clinical diagnosis and pharmacotherapy. Several NAFLD...
9.
Xu H, Li H, Tan W, Wang X, Zheng X, Huang Y, et al.
Sci Rep . 2024 Oct; 14(1):24578. PMID: 39427018
This study aimed to identify predictive factors for the prognosis of acute-on-chronic liver disease (AoCLD) due to both hepatitis B virus (HBV) and alcohol and to develop prognostic models to...
10.
Feng G, Mozes F, Ji D, Treeprasertsuk S, Okanoue T, Shima T, et al.
Clin Gastroenterol Hepatol . 2024 Oct; PMID: 39362618
Background & Aims: Metabolic dysfunction-associated steatohepatitis (MASH) and fibrotic MASH are significant health challenges. This multi-national study aimed to validate the acMASH index (including serum creatinine and aspartate aminotransferase concentrations)...