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Jing-Ya Wang

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Recent Articles
11.
Wang J, Ren P, Cui L, Duan J, Chen H, Zeng Z, et al.
Brain Behav Immun . 2024 Jun; 120:256-274. PMID: 38852761
Major depressive disorder (MDD) is a global health burden characterized by persistent low mood, deprivation of pleasure, recurrent thoughts of death, and physical and cognitive deficits. The current understanding of...
12.
Chang C, Yeh T, Chen C, Wang W, Chen Y, Tsai C, et al.
Mol Cancer Ther . 2024 Apr; 23(6):766-779. PMID: 38592383
Aurora kinase inhibitors, such as alisertib, can destabilize MYC-family oncoproteins and have demonstrated compelling antitumor efficacy. In this study, we report 6K465, a novel pyrimidine-based Aurora A inhibitor, that reduces...
13.
Gao K, Peng X, Wang J, Wang Y, Pei K, Meng X, et al.
Int J Biol Macromol . 2024 Apr; 266(Pt 2):131391. PMID: 38582456
Polysaccharides from Pinelliae Rhizoma Praeparatum Cum Alumine (PPA) have various biological activities, but their properties after oral administration are not clear. In this study, the absorption, digestion and fermentation properties...
14.
Ren P, Wang J, Chen H, Wang Y, Cui L, Duan J, et al.
J Pharmacol Sci . 2024 Mar; 154(4):236-245. PMID: 38485341
Postpartum depression (PPD) is a significant contributor to maternal morbidity and mortality. The Sigma-1 (σ-1) receptor has received increasing attention in recent years because of its ability to link different...
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16.
Liu Y, Gao K, Peng X, Wang Y, Wang J, Hu M
Int J Biol Macromol . 2024 Jan; 260(Pt 1):129431. PMID: 38237839
Despite significant progress in diagnosis and treatment, asthma remains a serious public health challenge. The conventional therapeutic drugs for asthma often have side effects and unsatisfactory clinical efficacy. Therefore, it...
17.
Wang J, Zhang F, Li X, Zhu K, Zuo N, Wang J, et al.
J Agric Food Chem . 2023 Oct; 71(44):16715-16726. PMID: 37889105
Zearalenone (ZEN) is well known as a kind of endocrine disruptor whose exposure is capable of causing reproductive toxicity in animals. Cyanidin-3--glucoside (C3G) is a derivative of cyanidin and owns...
18.
Chang P, Wang J, Wang W, Huang W, Wu M, Song J, et al.
Bioorg Med Chem . 2023 Oct; 95:117502. PMID: 37866089
A structure-activity relationship (SAR) study of stimulator of interferon gene (STING) inhibition was performed using a series of indol-3-yl-N-phenylcarbamic amides and indol-2-yl-N-phenylcarbamic amides. Among these analogs, compounds 10, 13, 15,...
19.
Zhang F, Zhu K, Wang J, Zhang M, Yan J, Liu Q, et al.
J Hazard Mater . 2023 Aug; 459:132226. PMID: 37549580
Zearalenone (ZEN) is a widespread and transgenerational toxicant that can cause serious reproductive health risks, which poses a potential threat to global agricultural production and human health; its estrogenic activity...
20.
Wang X, Wang J, Chen M, Ren J, Zhang X
World J Gastrointest Oncol . 2023 Aug; 15(7):1253-1261. PMID: 37546561
Background: Bones are one of the most common target organs for cancer metastasis. Early evaluation of bone metastasis (BM) status is clinically significant. Cancer patients often experience a hypercoagulable state....