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Jin-Li Luo

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Articles 11
Citations 141
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Recent Articles
1.
Zhang M, Bzura A, Baitei E, Zhou Z, Spicer J, Poile C, et al.
Nat Commun . 2024 Aug; 15(1):7187. PMID: 39168966
Malignant mesothelioma is a rare tumour caused by asbestos exposure that originates mainly from the pleural lining or the peritoneum. Treatment options are limited, and the prognosis is dismal. Although...
2.
Zhou L, Luo J, Sun A, Yang H, Lin Y, Han L
J Ethnopharmacol . 2023 Dec; 323:117689. PMID: 38160869
Ethnopharmacological Relevance: Autoimmune Thyroiditis (AIT) is a common refractory autoimmune disease of the endocrine system that may eventually lead to complete loss of thyroid function, with subsequent severe effects on...
3.
Fennell D, Griffiths D, Eminton Z, Morgan-Fox A, Hill K, Ewings S, et al.
BMJ Open . 2023 Nov; 13(11):e073120. PMID: 37993149
Background: Malignant mesothelioma is a rapidly lethal cancer that has been increasing at an epidemic rate over the last three decades. Targeted therapies for mesothelioma have been lacking. A previous...
4.
Zhang M, Luo J, Sun Q, Harber J, Dawson A, Nakas A, et al.
Nat Commun . 2021 Jun; 12(1):3569. PMID: 34099722
No abstract available.
5.
Busacca S, Zhang Q, Sharkey A, Dawson A, Moore D, Waller D, et al.
Sci Rep . 2021 Apr; 11(1):7434. PMID: 33795785
We hypothesized that small molecule transcriptional perturbation could be harnessed to target a cellular dependency involving protein arginine methyltransferase 5 (PRMT5) in the context of methylthioadenosine phosphorylase (MTAP) deletion, seen...
6.
Zhang M, Luo J, Sun Q, Harber J, Dawson A, Nakas A, et al.
Nat Commun . 2021 Mar; 12(1):1751. PMID: 33741915
Malignant Pleural Mesothelioma (MPM) is typically diagnosed 20-50 years after exposure to asbestos and evolves along an unknown evolutionary trajectory. To elucidate this path, we conducted multi-regional exome sequencing of...
7.
Eastley N, Sommer A, Ottolini B, Neumann R, Luo J, Hastings R, et al.
Int J Mol Sci . 2020 Jul; 21(12). PMID: 32599895
Soft tissue sarcomas (STS) are rare, malignant tumours with a generally poor prognosis. Our aim was to explore the potential of cell free DNA (cfDNA) and circulating tumour DNA (ctDNA)...
8.
Piao C, Luo J, Jin D, Tang C, Wang L, Lian F, et al.
Chin Med . 2020 Jan; 14:58. PMID: 31892939
Introduction: (Dan-shen in pinyin), a classic Chinese herb, has been extensively used to treat diabetic retinopathy in clinical practice in China for many years. However, the pharmacological mechanisms of remain...
9.
Alexandrou C, Al-Aqbi S, Higgins J, Boyle W, Karmokar A, Andreadi C, et al.
Sci Rep . 2018 Aug; 8(1):12096. PMID: 30108309
Tumors deficient in the urea cycle enzymes argininosuccinate synthase-1 (ASS1) and ornithine transcarbamylase (OTC) are unable to synthesize arginine and can be targeted using arginine-deprivation therapy. Here, we show that...
10.
Eastley N, Ottolini B, Neumann R, Luo J, Hastings R, Khan I, et al.
Oncotarget . 2018 Mar; 9(12):10549-10560. PMID: 29535826
Following treatment 40% of soft tissue sarcoma (STS) patients suffer disease recurrence. In certain cancers circulating cell free DNA (cfDNA) and circulating tumour-derived DNA (ctDNA) characteristics correlate closely with disease...