Frank Dudbridge
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Explore the profile of Frank Dudbridge including associated specialties, affiliations and a list of published articles.
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182
Citations
13961
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Recent Articles
1.
Murrin O, Mounier N, Voller B, Tata L, Gallego-Moll C, Roso-Llorach A, et al.
EBioMedicine
. 2025 Feb;
113:105584.
PMID: 39919332
Background: Multimorbidity, the presence of two or more conditions in one person, is common but studies are often limited to observational data and single datasets. We address this gap by...
2.
Cai S, Dudbridge F
Genet Epidemiol
. 2024 Oct;
49(1):e22600.
PMID: 39445745
Genome-wide association studies (GWAS) have provided large numbers of genetic markers that can be used as instrumental variables in a Mendelian Randomisation (MR) analysis to assess the causal effect of...
3.
Zhang M, Bzura A, Baitei E, Zhou Z, Spicer J, Poile C, et al.
Nat Commun
. 2024 Aug;
15(1):7187.
PMID: 39168966
Malignant mesothelioma is a rare tumour caused by asbestos exposure that originates mainly from the pleural lining or the peritoneum. Treatment options are limited, and the prognosis is dismal. Although...
4.
Agarwal T, Lyngdoh T, Khadgawat R, Dudbridge F, Kinra S, Relton C, et al.
Int J Obes (Lond)
. 2024 Jul;
48(11):1552-1558.
PMID: 38971891
Background: Obesity is among the leading public health threats globally. Over the last few years, visceral adiposity index (VAI), and body adiposity index (BAI), derived from anthropometric, and biochemical measures,...
5.
Timmins I, Zaccardi F, Yates T, Dudbridge F
Sci Rep
. 2024 May;
14(1):9995.
PMID: 38693307
The aim of this study was to assess the causal relationship between habitual walking pace and cardiovascular disease risk using a Mendelian randomisation approach. We performed both one- and two-sample...
6.
Shrine N, Guyatt A, Erzurumluoglu A, Jackson V, Hobbs B, Melbourne C, et al.
Nat Genet
. 2024 Apr;
56(5):1032-1033.
PMID: 38641645
No abstract available.
7.
Timmins I, Dudbridge F
PLoS Genet
. 2024 Apr;
20(4):e1011212.
PMID: 38630784
Population differences in risk of disease are common, but the potential genetic basis for these differences is not well understood. A standard approach is to compare genetic risk across populations...
8.
Burns K, Mullin B, Moolhuijsen L, Laisk T, Tyrmi J, Cui J, et al.
BMC Genomics
. 2024 Feb;
25(1):208.
PMID: 38408933
Background: Polycystic ovary syndrome (PCOS) is a complex multifactorial disorder with a substantial genetic component. However, the clinical manifestations of PCOS are heterogeneous with notable differences between lean and obese...
9.
Dudbridge F
PLoS One
. 2024 Feb;
19(2):e0297874.
PMID: 38386684
Bayes factors for composite hypotheses have difficulty in encoding vague prior knowledge, as improper priors cannot be used and objective priors may be subjectively unreasonable. To address these issues I...
10.
Frach L, Barkhuizen W, Allegrini A, Ask H, Hannigan L, Corfield E, et al.
Mol Psychiatry
. 2024 Jan;
29(4):951-961.
PMID: 38225381
The aetiology of conduct problems involves a combination of genetic and environmental factors, many of which are inherently linked to parental characteristics given parents' central role in children's lives across...