Jimmy Alarcan
Overview
Explore the profile of Jimmy Alarcan including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
110
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Recent Articles
1.
The zebrafish embryo as a model for chemically-induced steatosis: A case study with three pesticides
Heusinkveld H, Zwart E, de Haan A, Braeuning A, Alarcan J, van der Ven L
Toxicology
. 2024 Aug;
508:153927.
PMID: 39151607
There is an increasing incidence and prevalence of fatty liver disease in the western world, with steatosis as the most prevalent variant. Known causes of steatosis include exposure to food-borne...
2.
Alarcan J, Braeuning A
EXCLI J
. 2024 May;
23:509-522.
PMID: 38741723
Phycotoxins are responsible for foodborne intoxications. Symptoms depend on the ingested toxins but mostly imply gastro-intestinal and neurological disorders. Importantly, humans are exposed to combinations of several phycotoxins, resulting in...
3.
Wurger L, Alarcan J, Braeuning A
Arch Toxicol
. 2024 Feb;
98(5):1311-1322.
PMID: 38416141
Marine biotoxins are a heterogenous group of natural toxins, which are able to trigger different types of toxicological responses in animals and humans. Health effects arising from exposure to marine...
4.
Vink M, Alarcan J, Martens J, Buma W, Braeuning A, Berden G, et al.
Chem Res Toxicol
. 2023 Dec;
37(1):81-97.
PMID: 38118149
Toxicological assessments of newly developed agrochemical agents consider chemical modifications and their metabolic and biotransformation products. To carry out an in silico hazard assessment, understanding the type of chemical modification...
5.
Sadrabadi F, Alarcan J, Sprenger H, Braeuning A, Buhrke T
Arch Toxicol
. 2023 Dec;
98(2):507-524.
PMID: 38117326
Per- and polyfluoroalkyl substances (PFAS) are environmental contaminants with various adverse health effects in humans including disruption of lipid metabolism. Aim of the present study was to elucidate the molecular...
6.
Rioux B, Mouterde L, Alarcan J, Abiola T, Vink M, Woolley J, et al.
Chem Sci
. 2023 Dec;
14(47):13962-13978.
PMID: 38075651
Sinapoyl malate, naturally present in plants, has proved to be an exceptional UV filter and molecular heater for plants. Although there are nowadays industrially relevant sustainable synthetic routes to sinapoyl...
7.
Karaca M, Fritsche K, Lichtenstein D, Vural O, Kreuzer K, Alarcan J, et al.
STAR Protoc
. 2023 Aug;
4(3):102500.
PMID: 37616165
Here, we present an in vitro test battery to analyze chemicals for their potential to induce liver triglyceride accumulation, a hallmark of liver steatosis. We describe steps for using HepG2...
8.
Wuerger L, Kudiabor F, Alarcan J, Templin M, Poetz O, Sieg H, et al.
Cells
. 2023 Mar;
12(5).
PMID: 36899906
Okadaic acid (OA) is a marine biotoxin that is produced by algae and accumulates in filter-feeding shellfish, through which it enters the human food chain, leading to diarrheic shellfish poisoning...
9.
Sprenger H, Kreuzer K, Alarcan J, Herrmann K, Buchmuller J, Marx-Stoelting P, et al.
Food Chem Toxicol
. 2022 Jun;
166:113212.
PMID: 35690182
Toxicological risk assessment is essential in the evaluation and authorization of different classes of chemical substances. Genotoxicity and mutagenicity testing are of highest priority and rely on established in vitro...
10.
Abiola T, Rioux B, Toldo J, Alarcan J, Woolley J, Turner M, et al.
Chem Sci
. 2022 Jan;
12(46):15239-15252.
PMID: 34976344
Light-to-heat conversion materials generate great interest due to their widespread applications, notable exemplars being solar energy harvesting and photoprotection. Another more recently identified potential application for such materials is in...