Jim P Boyce
Overview
Explore the profile of Jim P Boyce including associated specialties, affiliations and a list of published articles.
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5
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46
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Recent Articles
1.
Dartois V, Bonfield T, Boyce J, Daley C, Dick T, Gonzalez-Juarrero M, et al.
Tuberculosis (Edinb)
. 2024 May;
147:102503.
PMID: 38729070
Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, is increasingly recognized as an important pathogen of the human lung, disproportionally affecting people with cystic fibrosis (CF) and other susceptible individuals with...
2.
Sharma K, Malik A, Roof R, Boyce J, Verma S
Drug Discov Today
. 2024 Mar;
29(4):103942.
PMID: 38447929
Despite successes with new drug approvals over the past two decades through conventional drug development approaches, many human diseases remain intractable to current therapeutic interventions. Possible barriers may be that...
3.
Park S, Casalena D, Wilson D, Dai R, Nag P, Liu F, et al.
Chem Biol
. 2015 Jan;
22(1):76-86.
PMID: 25556942
Biotin biosynthesis is essential for survival and persistence of Mycobacterium tuberculosis (Mtb) in vivo. The aminotransferase BioA, which catalyzes the antepenultimate step in the biotin pathway, has been established as...
4.
Boyce J, Brown M, Chin W, Fitzner J, Paxton R, Shen M, et al.
Bioconjug Chem
. 2008 Sep;
19(9):1775-84.
PMID: 18763820
Salicylanilides were found as selective inhibitors of interleukin-12p40 production in stimulated dendritic cells. The conversion of one of these bioactive salicylanilides into a comparably bioactive, chemically labeled derivative was achieved...
5.
Brown M, Fitzner J, Stevens T, Chin W, Wright C, Boyce J
Bioorg Med Chem
. 2008 Aug;
16(18):8760-4.
PMID: 18715785
Interleukin (IL)-12p40, a subunit component of both IL-12 and IL-23, is being widely studied for its role in inflammatory disease. As part of an effort to profile cellular signaling pathways...