Jim A Rotolo
Overview
Explore the profile of Jim A Rotolo including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
10
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0
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Recent Articles
1.
Exponential Combination of and Intracellular Peptide Libraries Identifies a Selective ATF3 Inhibitor
Yu M, Tang T, Ghamsari L, Yuen G, Scuoppo C, Rotolo J, et al.
ACS Chem Biol
. 2024 Feb;
19(3):753-762.
PMID: 38412264
Activating transcription factor 3 (ATF3) is an activation transcription factor/cyclic adenosine monophosphate (cAMP) responsive element-binding (CREB) protein family member. It is recognized as an important regulator of cancer progression by...
2.
Darvishi E, Ghamsari L, Leong S, Ramirez R, Koester M, Gallagher E, et al.
Mol Cancer Ther
. 2022 Sep;
21(11):1632-1644.
PMID: 36121385
CCAAT/enhancer binding protein β (C/EBPβ) is a basic leucine zipper (bZIP) family transcription factor, which is upregulated or overactivated in many cancers, resulting in a gene expression profile that drives...
3.
Yu M, Ghamsari L, Rotolo J, Kappel B, Mason J
RSC Chem Biol
. 2021 Aug;
2(2):656-668.
PMID: 34458807
To date, most research into the inhibition of oncogenic transcriptional regulator, Activator Protein 1 (AP-1), has focused on heterodimers of cJun and cFos. However, the Fra1 homologue remains an important...