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Jiebo Huang

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Articles 6
Citations 116
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Recent Articles
1.
Li S, Wang J, Chen Y, Cheng Y, Wang Y, Xu N, et al.
Inflammation . 2025 Mar; PMID: 40067577
Diabetic kidney disease (DKD), a leading cause of end-stage renal disease (ESRD), poses a serious threat to global health. Aseptic inflammation and pyroptosis of podocytes are crucial factors contributing to...
2.
Chen Y, Tao J, He Y, Hou X, Fang J, Huang J, et al.
Arch Pharm Res . 2024 Nov; 47(12):924-939. PMID: 39607647
Among the complications of diabetes, diabetic kidney disease (DKD) frequently emerges, typified by the detrimental effects on renal function, manifesting through inflammation, dysregulated lipid metabolism, and harm to podocytes. Existing...
3.
Yao X, Guo H, Sun M, Meng S, Zhu B, Fang J, et al.
J Diabetes Res . 2022 Apr; 2022:1329380. PMID: 35480629
Podocyte damage is vital for the etiopathogenesis of diabetic nephropathy (DN). Klotho (KL), a multifunctional protein, has been demonstrated to have renoprotective effects; nevertheless, the mechanism for protective effect has...
4.
Xing L, Fang J, Zhu B, Wang L, Chen J, Wang Y, et al.
Life Sci . 2021 Jan; 269:119068. PMID: 33476631
Aims: Podocyte apoptosis plays an important role in the pathogenesis of diabetic nephropathy (DN). Astragaloside IV (AS-IV) has been shown to protect against podocyte apoptosis. Here we aim to investigate...
5.
Xing L, Guo H, Meng S, Zhu B, Fang J, Huang J, et al.
Biochem Biophys Res Commun . 2020 Dec; 534:450-456. PMID: 33256980
Oxidative stress plays a key role in the pathogenesis of diabetic nephropathy (DN). The anti-aging protein Klotho has been demonstrated to have antioxidant capacity. Nuclear factor-erythroid 2-related factor 2 (Nrf2)...
6.
Fang J, Yao X, Hou M, Duan M, Xing L, Huang J, et al.
Biochem Biophys Res Commun . 2020 Apr; 527(2):466-473. PMID: 32336543
The genetic variations of the apolipoprotein L1 (APOL1) gene are associated with non-diabetic kidney diseases. However, very little is known about the role of ApoL1 in glomerular damage. Here, we...
7.
Xu Y, Gao H, Hu Y, Fang Y, Qi C, Huang J, et al.
Exp Cell Res . 2019 Jun; 382(2):111463. PMID: 31247189
Diabetic nephrology (DN) is attributed largely to the depletion of podocytes, which is closely associated to apoptosis. However, the complex mechanism of podocyte loss in DN pathogenesis remains unclear. Recently,...