Jie J Zhou
Overview
Explore the profile of Jie J Zhou including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
136
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0
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Recent Articles
1.
Wei Z, Xu Z, Liu X, Lo W, Ye F, Lau C, et al.
Nucleic Acids Res
. 2016 Jan;
44(3):1247-55.
PMID: 26773056
Many human tRNA synthetases evolved alternative functions outside of protein synthesis. These functions are associated with over 200 splice variants (SVs), most of which are catalytic nulls that engender new...
2.
Lo W, Gardiner E, Xu Z, Lau C, Wang F, Zhou J, et al.
Science
. 2014 Jul;
345(6194):328-32.
PMID: 25035493
Genetic efficiency in higher organisms depends on mechanisms to create multiple functions from single genes. To investigate this question for an enzyme family, we chose aminoacyl tRNA synthetases (AARSs). They...
3.
Zhou J, Wang F, Xu Z, Lo W, Lau C, Chiang K, et al.
J Biol Chem
. 2014 Jun;
289(28):19269-75.
PMID: 24898250
Inflammatory and debilitating myositis and interstitial lung disease are commonly associated with autoantibodies (anti-Jo-1 antibodies) to cytoplasmic histidyl-tRNA synthetase (HisRS). Anti-Jo-1 antibodies from different disease-afflicted patients react mostly with spatially...
4.
Xu Z, Wei Z, Zhou J, Ye F, Lo W, Wang F, et al.
Structure
. 2012 Sep;
20(9):1470-7.
PMID: 22958643
Aminoacyl-tRNA synthetases (AARSs) catalyze aminoacylation of tRNAs in the cytoplasm. Surprisingly, AARSs also have critical extracellular and nuclear functions. Evolutionary pressure for new functions might be manifested by splice variants...
5.
Li P, Zhou J, Meng M, Madhavan R, Peng H
PLoS One
. 2012 Sep;
7(9):e44759.
PMID: 22957106
Background: The assembly of the vertebrate neuromuscular junction (NMJ) is initiated when nerve and muscle first contact each other by filopodial processes which are thought to enable close interactions between...