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Jie Cen

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Articles 31
Citations 80
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Recent Articles
1.
Chen M, Cen J, Shi Q, Shao B, Tan J, Ye X, et al.
Angew Chem Int Ed Engl . 2025 Jan; 64(10):e202500878. PMID: 39878170
Lipid nanoparticles (LNPs) based messenger RNA (mRNA) therapeutics hold immense promise for treating a wide array of diseases, while their nonhepatic organs targeting and insufficient endosomal escape efficiency remain challenges....
2.
Song R, Tan J, Cen J, Li Z, Zhang Y, Hou M, et al.
J Am Chem Soc . 2025 Jan; 147(3):2889-2901. PMID: 39780364
Thiol-maleimide (MI) chemistry is a cornerstone of bioconjugation strategies, particularly in the development of drug delivery systems. The cyclic arginine-glycine-aspartic acid (cRGD) peptide, recognized for its ability to target the...
3.
Cen J, Liu W, Xu J, Wang X, Zhang J, Zhang J, et al.
Angew Chem Int Ed Engl . 2024 Sep; 64(3):e202415588. PMID: 39305234
Electron beam (EB) and extreme ultraviolet (EUV) lithography are advanced techniques capable of achieving sub-10 nm resolutions, critical for fabricating next-generation nanostructures and semiconductor devices. However, developing EUV photoresists that...
4.
Cen J, Hou M, Hu J, Liu S
Chemistry . 2024 Jul; 30(56):e202401911. PMID: 39079912
In the realm of biological macromolecules, entities such as nucleic acids and proteins are distinguished by their homochirality, consistently defined chain lengths, and integral sequence-dependent functionalities. Historically, these refined attributes...
5.
Wang H, Zhou Y, Lu L, Cen J, Wu Z, Yang B, et al.
ACS Med Chem Lett . 2024 Jul; 15(7):1143-1150. PMID: 39015274
amplification is frequently observed in approximately 50% of human cancers, rendering it a highly desired anticancer target. Given the challenge of direct pharmacological inhibiting of MYC, impairing the interaction of...
6.
Zhang H, Xiong X, Guo K, Zheng M, Cao T, Yang Y, et al.
Nat Commun . 2024 Jul; 15(1):5578. PMID: 38956103
Diatoms often outnumber other eukaryotic algae in the oceans, especially in coastal environments characterized by frequent fluctuations in light intensity. The identities and operational mechanisms of regulatory factors governing diatom...
7.
Liu H, Su H, Chen N, Cen J, Tan J, Zhang B, et al.
Angew Chem Int Ed Engl . 2024 Apr; 63(24):e202405314. PMID: 38602843
Ice has been suggested to have played a significant role in the origin of life partly owing to its ability to concentrate organic molecules and promote reaction efficiency. However, the...
8.
Yu X, Wang M, Cen J, Ye M, Li S, Wang Y, et al.
Afr Health Sci . 2024 Jan; 23(2):374-379. PMID: 38223627
Background: Tobacco dependence has become a global public health concern. We chose to investigate the modifiable factors and motivations during the period of smoking cessation based on the mechanism of...
9.
Wei C, Shi M, Dong S, Li Z, Zhao B, Liu D, et al.
Int J Biol Sci . 2024 Jan; 20(2):585-605. PMID: 38169591
Sirtuin 5 (SIRT5), localized in the mitochondria, has been identified as a protein desuccinylase and demalonylase in the mitochondria since the depletion of SIRT5 boosted the global succinylation and malonylation...
10.
Cen J, Zhu H, Hong C, Zhang X, Liu S, Yang B, et al.
Eur J Med Chem . 2023 Nov; 263:115933. PMID: 37976703
The important role of accumulated iron is well recognized in the pathophysiology of rhabdomyolysis-induced acute kidney injury (RM-AKI). Our previous work further confirmed the labile iron triggered iron-dependent ferroptosis thus...