Jiaxiong Lu
Overview
Explore the profile of Jiaxiong Lu including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
195
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Recent Articles
11.
Yu Y, Zhao Y, Fan Y, Chen Z, Li H, Lu J, et al.
Mol Cancer Ther
. 2019 Apr;
18(6):1045-1056.
PMID: 30962318
Neuroblastoma is the most common extracranial malignant solid tumor in children, and drug resistance is a major reason for poor outcomes. Elevated proteasome activity plays an important role in neuroblastoma...
12.
Wang M, Liang L, Lu J, Yu Y, Zhao Y, Shi Z, et al.
Thorac Cancer
. 2019 Mar;
10(4):918-929.
PMID: 30883017
Background: Delanzomib, a novel proteasome inhibitor, has demonstrated promising efficacy and antitumor ability in human multiple myeloma cell lines and patient-derived cells. However, the potential therapeutic effects of delanzomib on...
13.
Li Q, Hu H, Triapitsyn S, Yi L, Lu J
Zookeys
. 2018 Apr;
(736):43-57.
PMID: 29674867
A new Palaearctic species of Haliday (Hymenoptera, Mymaridae), A. (Anagrus) dmitrievi Triapitsyn & Hu, , is described, diagnosed, and illustrated from Xinjiang Uyghur Autonomous Region of China. It was reared...
14.
Guan S, Lu J, Zhao Y, Yu Y, Li H, Chen Z, et al.
Oncotarget
. 2018 Feb;
9(2):2591-2602.
PMID: 29416794
Maternal embryonic leucine zipper kinase (MELK) is known to modulate intracellular signaling and control cellular processes. However, the role of MELK in oncogenesis is not well defined. In this study,...
15.
Guo K, Han L, Li X, Yang A, Lu J, Guan S, et al.
Oncotarget
. 2018 Jan;
8(69):114123-114135.
PMID: 29371974
Cervical cancer, the third most commonly occurring cancer, is the second leading cause of cancer related mortality among women. Aberrant ubiquitination and proteasome activity, both human papillomavirus and tumor derived,...
16.
Lu J, Guan S, Zhao Y, Yu Y, Woodfield S, Zhang H, et al.
Cancer Lett
. 2017 Apr;
400:61-68.
PMID: 28455243
Activating germline mutations of anaplastic lymphoma kinase (ALK) occur in most cases of hereditary neuroblastoma (NB) and the constitutively active kinase activity of ALK promotes cell proliferation and survival in...
17.
Guan S, Lu J, Zhao Y, Woodfield S, Zhang H, Xu X, et al.
Oncotarget
. 2017 Apr;
8(20):33666-33675.
PMID: 28430599
Aberrant activation of nuclear factor-κB (NF-κB) allows cancer cells to escape chemotherapy-induced cell death and acts as one of the major mechanisms of acquired chemoresistance in cervical cancer. TAK1, a...
18.
Mao X, Chen Z, Zhao Y, Yu Y, Guan S, Woodfield S, et al.
Oncotarget
. 2016 Dec;
8(1):1555-1568.
PMID: 27902463
Neuroblastoma is the most common extracranial solid tumor in children. The ErbB family of proteins is a group of receptor tyrosine kinases that promote the progression of various malignant cancers...
19.
Lu J, Guan S, Zhao Y, Yu Y, Wang Y, Shi Y, et al.
Oncotarget
. 2016 Oct;
7(50):82757-82769.
PMID: 27764791
Neuroblastoma (NB), which accounts for about 15% of cancer-related mortality in children, is the most common childhood extracranial malignant tumor. In NB, somatic mutations of the tumor suppressor, p53, are...
20.
Guan S, Zhao Y, Lu J, Yu Y, Sun W, Mao X, et al.
Oncotarget
. 2016 Oct;
7(46):75914-75925.
PMID: 27713150
Neuroblastoma (NB), which accounts for about 15% of cancer-related mortality in children, is the most common extracranial malignant neoplasm in children. Elevated level of proteasome activity promotes cancer development and...