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Jiaxin Huang

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Articles 135
Citations 808
Followers 0
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Recent Articles
1.
Han Z, Huang J, Shang P, Zhu X, Huang H, Sun J
Org Lett . 2025 Mar; PMID: 40073294
2-Quinolones represent a versatile class of compounds that are prevalent in natural and medicinally relevant molecules. Here we report a new approach to the selective formation of these structures. By...
2.
Huang J, Yang J, Yang Y, Lu X, Xu J, Lu S, et al.
Adv Sci (Weinh) . 2025 Mar; :e2415227. PMID: 40052211
Doxorubicin (Dox) is a potent chemotherapeutic agent commonly used in cancer treatment. However, cardiotoxicity severely limited its clinical application. To address this challenge, a novel self-assembled nanomedicine platform, PMDDH, is...
3.
Shao C, Lan W, Ding Y, Ye L, Huang J, Liang X, et al.
Phytomedicine . 2025 Feb; 139:156501. PMID: 39978277
Background: Hepatic fibrosis (HF) is an intermediate stage in the progression of chronic liver disease to cirrhosis and has been shown to be a reversible pathological process. Known evidence suggests...
4.
Wu Z, Zhang G, Shang Y, Huang J, Liu Y, Zhou H, et al.
Bioorg Med Chem . 2025 Feb; 121:118078. PMID: 39965986
Previous experiments have revealed that curcumin exerts potential antitumor effect by inducing apoptosis and ferroptosis of tumor cells. However, its low solubility and bioavailability, as well as fast metabolism limit...
5.
Xiang P, Marat T, Huang J, Cheng B, Liu J, Wang X, et al.
BMC Plant Biol . 2025 Feb; 25(1):199. PMID: 39953393
Background: Epigallocatechin gallate (EGCG) imparts unique health benefits and flavour to tea. Photosynthesis plays a crucial role in modulating secondary metabolite production in plants, and this study investigated its impact...
6.
Peng Q, Huang J, Li S, Chen Z, Zhu Q, Yuan H, et al.
Food Res Int . 2025 Jan; 201():115609. PMID: 39849759
Ningxia Goji Berry Wine (NGBW), a traditional Chinese fermented beverage, exhibits complex flavor quality changes during fermentation, the mechanisms of which remain insufficiently elucidated. This study aimed to elucidate the...
7.
Liu X, Huang J, Zhou H, Wang S, Guo X, Mao J, et al.
Biomaterials . 2025 Jan; 317:123116. PMID: 39848004
Nowadays, photodynamic therapy (PDT) offers a non-invasive tumor treatment with high safety profiles and minimal side effects, implying a promising clinical application for patients with malignant tumors. However, the lack...
8.
Lu Y, Shan X, Huang J, Zhou H, Zhu Y, Wang S, et al.
ACS Nano . 2025 Jan; 19(4):4195-4212. PMID: 39846120
Atopic dermatitis (AD) is a recurrent and chronic inflammatory skin condition characterized by a high lifetime prevalence and significant impairment of patients' quality of life, primarily due to intense itching...
9.
He Y, Huang J, Liang X, Shao C, Sun X, Zhang J
Heliyon . 2025 Jan; 11(1):e41346. PMID: 39811369
Background: The vascular endothelial growth factor (VEGF) signaling pathway is closely related to pathological angiogenesis in liver disease. Anti-angiogenesis is an effective intervention in the clinical treatment of liver disease....
10.
Zhao X, Yu Y, Xu X, Zhang Z, Chen Z, Gao Y, et al.
Adv Mater . 2025 Jan; 37(9):e2417536. PMID: 39801185
Ulcerative colitis (UC) is a chronic gastrointestinal inflammatory disorder with rising prevalence. Due to the recurrent and difficult-to-treat nature of UC symptoms, current pharmacological treatments fail to meet patients' expectations....