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Jianyuan Chai

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Citations 305
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Recent Articles
1.
Xing L, Jiang Z, Xu R, Dang T, Wu J, Chai J, et al.
Sci Rep . 2025 Jan; 15(1):1808. PMID: 39806221
CCN1 is a matricellular protein highly expressed in esophageal squamous cell carcinoma (ESCC) but hardly detectable in esophageal adenocarcinoma (EAC). Expression of CCN1 in EAC cells leads to TRAIL-mediated apoptosis....
2.
Xu R, Jiang Z, Meng X, Xing L, Aladan W, Chi B, et al.
J Cell Commun Signal . 2024 Nov; 18(3):e12046. PMID: 39524140
Induction of apoptosis in tumor cells is one of the best ways to cure cancer. While most apoptosis requires a chain of caspase activation, CASP2 can do this all by...
3.
Tang B, Jia Y, Dang T, Chai J, Wang Q, Chang Z, et al.
Dig Dis . 2022 Sep; 41(2):325-334. PMID: 36063790
Background And Aims: Choledochoscopic gallbladder-preserving surgery (CGPS) has the advantage of treating benign gallbladder diseases on the premise of gallbladder preservation. However, it has no reliable preoperative diagnosis if the...
4.
Wang P, Chang Z, Meng J, Cui X, Chai J, Dang T
Cell Signal . 2022 Jun; 96:110374. PMID: 35654297
Esophageal cancer is commonly seen as either squamous cell carcinoma (ESCC) or adenocarcinoma (EAC), two very different cancers. CCN1 is a matricellular protein that induces apoptosis in EAC cells through...
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Cui X, Chang Z, Dang T, Meng J, Wang P, Wu J, et al.
Arch Biochem Biophys . 2022 Apr; 722:109192. PMID: 35367194
TNF, CCN1, and peptidoglycan recognition protein 1 (PGLYRP1) are often found together in the inflammatory tissue. While TNF and CCN1 promote tissue regeneration, PGLYRP1 protects it from bacterial infection. In...
7.
Chang Z, Dang T, Meng X, Chai J
Cancer Control . 2022 Mar; 29:10732748221074734. PMID: 35291889
: Esophageal cancer is one of the most common and deadliest cancers in the world, particularly esophageal adenocarcinoma. There has never been a special drug to treat it.: This article...
8.
Meng X, Dang T, Chai J
Cancer Control . 2021 Dec; 28:10732748211066311. PMID: 34913371
DNA mutation is a common event in the human body, but in most situations, it is fixed right away by the DNA damage response program. In case the damage is...
9.
Dang T, Chang Z, Meng J, Cui X, Wang P, Chai J
Cytokine . 2021 Oct; 149:155728. PMID: 34634651
TNF signaling mostly supports cell growth by activating NFκB and only induces cell death when NFκB activation fails. CCN1 is a matricellular protein that has been reported capable to convert...
10.
Wu J, Meng X, Gao R, Jia Y, Chai J, Zhou Y, et al.
Exp Cell Res . 2020 Aug; 396(1):112214. PMID: 32768499
Accumulating evidence shows the involvement of long non-coding RNAs (lncRNAs) in tumorigenesis of many types of human cancers. However, the role of LINC00858 in colon cancer has not been fully...