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Jianting Zheng

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Articles 42
Citations 377
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Recent Articles
1.
Wang Y, Tian Y, Yang X, Yu F, Zheng J
Nat Commun . 2025 Mar; 16(1):2408. PMID: 40069208
Bacterial antiviral STANDs (Avs) are evolutionarily related to the nucleotide-binding oligomerization domain (NOD)-like receptors widely distributed in immune systems across animals and plants. EfAvs5, a type 5 Avs from Escherichia...
2.
Yang X, Wang Y, Zheng J
Int J Biol Macromol . 2024 Jul; 277(Pt 1):134145. PMID: 39059542
Bacterial defense-associated sirtuin 2 (DSR2) proteins harbor an N-terminal sirtuin (SIR2) domain degrading NAD. DSR2 from Bacillus subtilis 29R is autoinhibited and unable to hydrolyze NAD in the absence of...
3.
Huang S, Ji H, Zheng J
FEBS J . 2024 Jun; 291(17):3839-3855. PMID: 38922792
Polyketides are natural products synthesized by polyketide synthases (PKSs), where acyltransferase (AT) domains play a crucial role in selection of extender units. Engineering of AT domains enables the site-specific incorporation...
4.
Xiao Z, Zha J, Yang X, Huang T, Huang S, Liu Q, et al.
Nat Commun . 2024 Mar; 15(1):2128. PMID: 38459030
Modulation of protein function through allosteric regulation is central in biology, but biomacromolecular systems involving multiple subunits and ligands may exhibit complex regulatory mechanisms at different levels, which remain poorly...
5.
Wang Y, Yang X, Yu F, Deng Z, Lin S, Zheng J
PLoS Biol . 2024 Mar; 22(3):e3002528. PMID: 38427710
Streptomyces antibiotic regulatory proteins (SARPs) are widely distributed activators of antibiotic biosynthesis. Streptomyces coelicolor AfsR is an SARP regulator with an additional nucleotide-binding oligomerization domain (NOD) and a tetratricopeptide repeat...
6.
Ali I, Wei D, Khan A, Feng Y, Waseem M, Hussain Z, et al.
Biotechnol Appl Biochem . 2024 Jan; 71(2):402-413. PMID: 38287712
Malonyl-CoA serves as the main building block for the biosynthesis of many important polyketides, as well as fatty acid-derived compounds, such as biofuel. Escherichia coli, Corynebacterium gultamicum, and Saccharomyces cerevisiae...
7.
Huang S, Ji H, Zheng J
Int J Biol Macromol . 2023 Sep; 253(Pt 3):126763. PMID: 37703985
Rhamnose methylation of spinosyn critical for insecticidal activity is orchestrated by substrate specificity of three S-adenosyl-L-methionine (SAM) dependent methyltransferases (MTs). Previous in vitro enzymatic assays indicate that 3'-O-MT SpnK accepts...
8.
Hao Z, Guo Q, Feng Y, Zhang Z, Li T, Tian Z, et al.
JACS Au . 2023 Sep; 3(8):2144-2155. PMID: 37654596
The soluble N-glycosyltransferase from (ApNGT) can establish an N-glycosidic bond at the asparagine residue in the Asn-Xaa-Ser/Thr consensus sequon and is one of the most promising tools for N-glycoprotein production....
9.
Liu R, Chen X, Zhao F, Jiang Y, Lu Z, Ji H, et al.
J Fungi (Basel) . 2023 Jun; 9(6). PMID: 37367608
The Complex of Proteins Associated with Set1 (COMPASS) methylates lysine K4 on histone H3 (H3K4) and is conserved from yeast to humans. Its subunits and regulatory roles in the meningitis-causing...
10.
Zhu C, Liang X, Chen X, Liang M, Zheng J, Wan B, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768882
Gametogenesis is an essential step for malaria parasite transmission and is activated in mosquito by signals including temperature drop, pH change, and mosquito-derived xanthurenic acid (XA). Recently, a membrane protein...