Jiangning Chen
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Explore the profile of Jiangning Chen including associated specialties, affiliations and a list of published articles.
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103
Citations
4298
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Recent Articles
1.
Ji S, Wang F, Wu Y, Hu H, Xing Z, Zhu J, et al.
Sci Adv
. 2025 Jan;
11(5):eado5600.
PMID: 39888994
Precise neoepitope discovery is crucial for effective cancer therapeutic vaccines. Conventional approaches struggle to build a repertoire with sufficient immunogenic epitopes. We developed a workflow leveraging full-length ribosome-nascent chain complex-bound...
2.
Cheng X, Shao P, Wang X, Jiang J, Chen J, Zhu J, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(8):e2411711.
PMID: 39739231
Intestinal fibrosis, a severe complication of Crohn's disease (CD), is linked to chronic inflammation, but the precise mechanism by which immune-driven intestinal inflammation leads to fibrosis development is not fully...
3.
Li W, Ding J, Chen S, Chen J, Wang C, Li J, et al.
J Control Release
. 2024 Oct;
376:123-137.
PMID: 39378978
Inflammatory bowel disease (IBD) is a group of chronic relapsing diseases associated with inflammatory disorders and microbial dysbiosis of the intestine. The use of traditional Chinese medicine (TCM) to treat...
4.
He Y, Wang W, Jiang J, Shen Y, Wang B, Chen J, et al.
Heliyon
. 2024 Jul;
10(12):e33146.
PMID: 38994066
Background: Acne inversa (AI) is a refractory inflammatory skin disease, and TNF-α plays an important role in the pathogenesis of AI. By blocking TNF-α, infliximab (IFX) has been proven to...
5.
Wang H, Zhao J, Ji S, Liu T, Cheng Z, Huang Z, et al.
Free Radic Biol Med
. 2024 May;
220:236-248.
PMID: 38704052
Alcoholic liver disease (ALD) is a common chronic redox disease caused by increased alcohol consumption. Abstinence is a major challenge for people with alcohol dependence, and approved drugs have limited...
6.
Zhao M, Cheng X, Shao P, Dong Y, Wu Y, Xiao L, et al.
Nat Commun
. 2024 Jan;
15(1):950.
PMID: 38296939
The CRISPR-Cas9 system offers substantial potential for cancer therapy by enabling precise manipulation of key genes involved in tumorigenesis and immune response. Despite its promise, the system faces critical challenges,...
7.
Sun Y, Ge J, Shao F, Ren Z, Huang Z, Ding Z, et al.
FASEB J
. 2023 Jun;
37(8):e23071.
PMID: 37389924
The sustained release of profibrotic cytokines, mainly transforming growth factor-β (TGF-β), leads to the occurrence of kidney fibrosis and chronic kidney disease (CKD). Connective tissue growth factor (CTGF) appears to...
8.
Sun Q, Xiao L, Cui Z, Yang Y, Ma J, Huang Z, et al.
Chin Med
. 2022 Jun;
17(1):81.
PMID: 35773674
Background: Immune checkpoint inhibitors that target programmed cell death protein 1 (PD-1) have obtained encouraging results, but a fraction of tumor patients failed to respond to anti-PD-1 treatment due to...
9.
Ye Y, Shi Q, Yang T, Xie F, Zhang X, Xu B, et al.
Technol Cancer Res Treat
. 2022 Mar;
21:15330338221085370.
PMID: 35315725
Tumor extracellular vesicles (EVs) and their relevance to various processes of tumor growth have been vigorously investigated over the past decade. However, obtaining direct evidence of spontaneous EV transfer remains...
10.
Sun Y, Cai H, Ge J, Shao F, Huang Z, Ding Z, et al.
J Pathol
. 2021 Sep;
256(1):25-37.
PMID: 34543458
Upstream stimuli for myofibroblast activation are of considerable interest for understanding the mechanisms underlying renal fibrosis. Activin B, a member of the TGF-β family, exists as a homodimer of inhibin...