Jian-Xin Jia
Overview
Explore the profile of Jian-Xin Jia including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
94
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Recent Articles
1.
Yao S, Xu Z, Guo W, Zhang H, Zhang M, Jia J, et al.
J Toxicol Environ Health A
. 2025 Mar;
:1-13.
PMID: 40056093
Parkinson's Disease (PD) a progressive neurodegenerative disorder is attributed to dopaminergic neuronal cell loss in the mid-brain substantia nigra pars compacta. A major risk factors associated with PD development is...
2.
Gao W, Lv X, Li H, Yan X, Huo D, Yang Z, et al.
J Toxicol Environ Health A
. 2025 Feb;
:1-11.
PMID: 39995113
Cerebral ischemia-reperfusion injury (CIRI) is a prevalent clinical complication associated with reperfusion following ischemic stroke resulting in neuronal damage and cognitive impairment. Dexmedetomidine (DEX), a highly selective α2-adrenoceptor agonist with...
3.
Ma B, Jia J, Wang H, Li S, Yang Z, Wang X, et al.
J Toxicol Environ Health A
. 2024 Apr;
87(11):471-479.
PMID: 38590254
Cannabidiol (CBD), a natural component extracted from . exerts neuroprotective, antioxidant, and anti-inflammatory effects in Alzheimer's disease (AD), a disease characterized by impaired cognition and accumulation of amyloid-B peptides (Aβ)....
4.
Ren W, Yan X, Fan J, Huo D, Wang X, Jia J, et al.
J Toxicol Environ Health A
. 2024 Apr;
87(10):436-447.
PMID: 38557424
One of the main pathological features noted in Alzheimer's disease (AD) is the presence of plagues of aggregated β-amyloid (Aβ1-42)-peptides. Excess deposition of amyloid-β oligomers (AβO) are known to promote...
5.
Wang L, Jia J, Zhang S, Song W, Yan X, Huo D, et al.
J Toxicol Environ Health A
. 2024 Apr;
87(10):448-456.
PMID: 38557302
Cerebral ischemia-reperfusion injury (CIRI) occurs frequently clinically as a complication following cardiovascular resuscitation resulting in neuronal damage specifically to the hippocampal CA1 region with consequent cognitive impairment. Apoptosis and oxidative...
6.
He J, Zhang H, Zheng H, Jia J, Zhang Y, Yan X, et al.
J Toxicol Environ Health A
. 2024 Mar;
87(10):421-427.
PMID: 38551405
Vascular dementia (VD) a heterogenous group of brain disorders in which cognitive impairment is attributable to vascular risk factors and cerebrovascular disease. A common phenomenon in VD is a dysfunctional...
7.
Liu S, Tang X, He F, Jia J, Hu H, Xie B, et al.
Nat Prod Res
. 2020 Nov;
36(9):2370-2378.
PMID: 33146025
Two new compounds, 6-acetyl-4-methoxy-3,5-dimethyl-2-pyran-2-one () and (2,4)-5-((2,3,4,5)-3,4-dihydroxy-2,4,5-trimethyltetrahydrofuran-2-yl)-2,4-dimethylpenta-2,4-dienal (), and 22 known compounds were identified from the mangrove-forest-derived fungus H175. The structures of these compounds were elucidated by analysis of the...
8.
Wang L, Pei J, Jia J, Wang J, Song W, Fang X, et al.
J Toxicol Environ Health A
. 2019 Nov;
82(20):1061-1068.
PMID: 31746286
It is well known that synaptic plasticity is associated with cognitive performance in Alzheimer's disease (AD). Testosterone (T) is known to exert protective effects on cognitive deficits in AD, but...
9.
Huo D, Sun J, Cai Z, Yan X, Wang H, Jia J, et al.
J Toxicol Environ Health A
. 2019 Nov;
82(19):1027-1035.
PMID: 31739751
Ginsenoside Rg1 (GsRg1), derived from the herb Ginseng, was found to exert protective effects in nerve injury; however, the mechanisms underlying these effects remain to be determined. Oxidant stress and...
10.
Wu P, Yan X, Zhou L, Liu X, Huo D, Song W, et al.
J Toxicol Environ Health A
. 2019 Nov;
82(19):1036-1044.
PMID: 31736438
An extract of (DML) was found to exert protective effects on cerebral ischemia-reperfusion injury (CIRI); however, the mechanisms underlying the observed actions of this plant-derived mixture remain to be determined....