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Jia-Yun Chen

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Recent Articles
11.
Luo P, Zhang Q, Zhong T, Chen J, Zhang J, Tian Y, et al.
Mil Med Res . 2022 May; 9(1):22. PMID: 35596191
Background: Sepsis involves life-threatening organ dysfunction and is caused by a dysregulated host response to infection. No specific therapies against sepsis have been reported. Celastrol (Cel) is a natural anti-inflammatory...
12.
Wu Z, Cai M, Huang P, Chen J, Lv Z, Huang X
Medicine (Baltimore) . 2021 Jun; 100(26):e26185. PMID: 34190145
Background: Primary dysmenorrhea (PD), one of the most common diseases in women, is known to be effective with object-separated moxibustion. However, because there is no large sample size for comparison,...
13.
Li C, Liu L, Zhao Y, Chen J, Sun X, Ouyang J
Oxid Med Cell Longev . 2021 Mar; 2021:6653593. PMID: 33747347
Three carboxymethylated polysaccharides (PCP-C1, PCP-C2, and PCP-C3) with -COOH contents of 6.13%, 10.24%, and 16.22%, respectively, were obtained by carboxymethylation of the original polysaccharide (PCP-C0), which has a molecular weight...
14.
Sun X, Zhang H, Chen J, Zeng G, Ouyang J
Mater Sci Eng C Mater Biol Appl . 2020 Dec; 119:111448. PMID: 33321587
Mineralization crystallization is considered to be the initial stage of stone formation. However, the formation of crystals and subsequent cell damage have rarely been investigated. An oxidatively damaged cell model...
15.
Gerosa L, Chidley C, Frohlich F, Sanchez G, Lim S, Muhlich J, et al.
Cell Syst . 2020 Oct; 11(5):478-494.e9. PMID: 33113355
Targeted inhibition of oncogenic pathways can be highly effective in halting the rapid growth of tumors but often leads to the emergence of slowly dividing persister cells, which constitute a...
16.
Sun X, Chen J, Rao C, Ouyang J
Int J Nanomedicine . 2020 Aug; 15:5043-5060. PMID: 32764935
Background: Hydroxyapatite (HAP) is a common component of most idiopathic calcium oxalate (CaOx) stones and is often used as a nidus to induce the formation of CaOx kidney stones. Methods:...
17.
Wang L, Zeng Y, Chen J, Luo Q, Wang R, Zhang R, et al.
Medicine (Baltimore) . 2020 Jun; 99(23):e20646. PMID: 32502051
It is critical to accurately identify patients with severe acute pancreatitis (SAP) in a timely manner. This study aimed to develop a new simplified AP scoring system based on data...
18.
Huang L, Liu H, Chen J, Sun X, Yao Z, Han J, et al.
Food Funct . 2020 Apr; 11(4):3393-3409. PMID: 32232300
Vascular calcification (VC) is a common pathological manifestation in patients with cardiovascular diseases, leading to high mortality in patients with chronic kidney diseases. The deposition of hydroxyapatite (HAP) crystals on...
19.
Chen J, Sun X, Ouyang J
Oxid Med Cell Longev . 2020 Feb; 2020:6982948. PMID: 32089775
Corn silk polysaccharide (CSP0; molecular weight = 124 kDa) was degraded by ultrasonication to obtain five degraded polysaccharides, namely, CSP1, CSP2, CSP3, CSP4, and CSP5, with molecular weights of 26.1,...
20.
Melms J, Vallabhaneni S, Mills C, Yapp C, Chen J, Morelli E, et al.
Cancer Res . 2019 Dec; 80(4):798-810. PMID: 31882401
Patients with melanoma resistant to RAF/MEK inhibitors (RMi) are frequently resistant to other therapies, such as immune checkpoint inhibitors (ICI), and individuals succumb to their disease. New drugs that control...