Ji-Hong Lim
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Explore the profile of Ji-Hong Lim including associated specialties, affiliations and a list of published articles.
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56
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2263
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Recent Articles
1.
Cho D, Han J, Kim I, Lim J, Ko H, Kim B, et al.
Sci Signal
. 2025 Mar;
18(876):eadp8973.
PMID: 40036356
Neuroinflammation promotes the progression of various neurological and neurodegenerative diseases. Disrupted homeostasis of protein acetylation is implicated in neurodegeneration, and the lysine acetyltransferase GCN5 (also known as KAT2A) is implicated...
2.
Lee J, Yang S, Park S, Kweon S, Ma G, Seo M, et al.
ACS Nano
. 2025 Jan;
19(2):2870-2889.
PMID: 39761412
The tumor-specific efficacy of the most current anticancer therapeutic agents, including antibody-drug conjugates (ADCs), oligonucleotides, and photosensitizers, is constrained by limitations such as poor cell penetration and low drug delivery....
3.
Lee K, Lee Y, Yang S, Lee J, Kim H, Lim J, et al.
J Control Release
. 2024 Jul;
372:885-900.
PMID: 38971425
Statins are widely used to treat hyperlipidemia; however, their mechanism-inhibiting cholesterol production without promoting its utilization-causes problems, such as inducing diabetes. In our research, we develop, for the first time,...
4.
Lim C, Fang X, Kang H, Oh T, Lee S, Kim Y, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474017
Ubiquitin-specific protease 7 inhibitors (USP7i) are considered a novel class of anticancer drugs. Cancer cells occasionally become insensitive to anticancer drugs, known as chemoresistance, by acquiring multidrug resistance, resulting in...
5.
Kim Y, Han J, Lim C, Fang X, Jang H, Lee S, et al.
Nutrients
. 2024 Jan;
16(2).
PMID: 38276543
Plant extract fermentation is widely employed to enhance the nutritional and pharmaceutical value of functional foods. (Pc) contains flavonoids, anthraquinones, and stilbenes, imparting protective effects against inflammatory diseases, cancer, diabetes,...
6.
Lee J, Yang S, Lee J, Lim H, Lee S, Kang T, et al.
Carbohydr Polym
. 2023 May;
314:120930.
PMID: 37173028
Heparin is a glycosaminoglycans (GAGs) member and well-known FDA-approved anticoagulant that has been widely used in the clinic for 100 years. It has also been evaluated in various fields for...
7.
Fang X, Lee S, Kim Y, Han G, Lim C, Lim J
Anticancer Res
. 2023 Feb;
43(3):1149-1157.
PMID: 36854496
Background/aim: Cachexia - a wasting disorder of adipose and skeletal muscle tissue - is the most common driver of poor prognosis in patients with advanced lung cancer. Parathyroid hormone-like hormone...
8.
Yoo H, Choi D, Roh Y, Lee Y, Lim J, Eo S, et al.
Cell Rep
. 2022 Nov;
41(6):111598.
PMID: 36351405
Classically activated pro-inflammatory macrophages are generated from naive macrophages by pro-inflammatory cues that dynamically reprogram their fuel metabolism toward glycolysis. This increases their intracellular reactive oxygen species (ROS) levels, which...
9.
Fang X, Lee M, Lim W, Lee S, Lim C, Lim J
Int J Mol Sci
. 2022 Jul;
23(15).
PMID: 35897813
The peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) is a critical transcriptional coactivator that maintains metabolic homeostasis and energy expenditure by cooperating with various transcription factors. Recent studies have shown...
10.
Fang X, Kim Y, Lee Y, Lee M, Lim W, Yim W, et al.
Nutrients
. 2022 Apr;
14(7).
PMID: 35406121
Cachexia, which is characterised by the wasting of fat and skeletal muscles, is the most common risk factor for increased mortality rates among patients with advanced lung cancer. (parathyroid hormone-like...