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Ji-Dong Fu

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Articles 37
Citations 3712
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Recent Articles
1.
Yang D, Wan X, Schwieterman N, Cavus O, Kacira E, Xu X, et al.
Circ Arrhythm Electrophysiol . 2023 Dec; 17(1):e012150. PMID: 38126205
Background: MicroRNA-1 (miR1), encoded by the genes and , is the most abundant microRNA in the heart and plays a critical role in heart development and physiology. Dysregulation of miR1...
2.
Kacira E, Pittman M, Yang D, Sturgill S, Ziolo M, Han Y, et al.
Circ Heart Fail . 2023 Dec; 17(1):e011046. PMID: 38054280
No abstract available.
3.
Vasireddi S, Sattayaprasert P, Yang D, Dennis A, Bektik E, Fu J, et al.
J Pers Med . 2022 Oct; 12(10). PMID: 36294819
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic disorder of desmosomal and structural proteins that is characterized by fibro-fatty infiltrate in the ventricles and fatal arrhythmia that can occur early...
4.
Feng Y, Cai L, Hong W, Zhang C, Tan N, Wang M, et al.
Circulation . 2022 Apr; 145(22):1663-1683. PMID: 35400201
Background: Transcriptional reconfiguration is central to heart failure, the most common cause of which is dilated cardiomyopathy (DCM). The effect of 3-dimensional chromatin topology on transcriptional dysregulation and pathogenesis in...
5.
Yang D, Deschenes I, Fu J
J Mol Cell Cardiol . 2022 Mar; 166:107-115. PMID: 35247375
The electrophysiological properties of the heart include cardiac automaticity, excitation (i.e., depolarization and repolarization of action potential) of individual cardiomyocytes, and highly coordinated electrical propagation through the whole heart. An...
6.
Yang M, Fu J, Zou J, Sridharan D, Zhao M, Singh H, et al.
Autophagy . 2022 Feb; 18(10):2481-2494. PMID: 35220905
Defective mitophagy contributes to normal aging and various neurodegenerative and cardiovascular diseases. The newly developed methodologies to visualize and quantify mitophagy allow for additional progress in defining the pathophysiological significance...
7.
Laurita K, Khan S, McMahon T, Dennis A, Li V, Gaivin R, et al.
Sci Rep . 2021 Oct; 11(1):20570. PMID: 34663875
Chronic kidney disease (CKD) affects more than 20 million people in the US, and it is associated with a significantly increased risk of sudden cardiac death (SCD). Despite the significance,...
8.
Bektik E, Sun Y, Dennis A, Sakon P, Yang D, Deschenes I, et al.
Cells . 2021 Jul; 10(7). PMID: 34206684
Direct cardiac reprogramming of fibroblasts into induced cardiomyocytes (iCMs) is a promising approach but remains a challenge in heart regeneration. Efforts have focused on improving the efficiency by understanding fundamental...
9.
Zheng Y, Wan X, Yang D, Ramirez-Navarro A, Liu H, Fu J, et al.
Front Physiol . 2021 Apr; 12:661429. PMID: 33828490
Na1.5, encoded by the gene , is the predominant voltage-gated sodium channel expressed in the heart. It initiates the cardiac action potential and thus is crucial for normal heart rhythm...
10.
Yang D, Wan X, Dennis A, Bektik E, Wang Z, Costa M, et al.
Circulation . 2021 Feb; 143(16):1597-1613. PMID: 33590773
Background: MicroRNAs (miRs) play critical roles in regulation of numerous biological events, including cardiac electrophysiology and arrhythmia, through a canonical RNA interference mechanism. It remains unknown whether endogenous miRs modulate...