Jesus D Rosado-Lugo
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Explore the profile of Jesus D Rosado-Lugo including associated specialties, affiliations and a list of published articles.
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6
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68
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Recent Articles
1.
Sagong H, Rosado-Lugo J, Bryan E, Ferrer-Gonzalez E, Wang Y, Cao Y, et al.
Med Chem Res
. 2023 Apr;
31(10):1679-1704.
PMID: 37077288
MreB is a cytoskeleton protein present in rod-shaped bacteria that is both essential for bacterial cell division and highly conserved. Because most Gram (-) bacteria require MreB for cell division,...
2.
Zhang Y, Rosado-Lugo J, Datta P, Sun Y, Cao Y, Banerjee A, et al.
Antibiotics (Basel)
. 2022 Jun;
11(6).
PMID: 35740123
Efflux pumps in Gram-negative bacteria such as Pseudomonas aeruginosa provide intrinsic antimicrobial resistance by facilitating the extrusion of a wide range of antimicrobials. Approaches for combating efflux-mediated multidrug resistance involve,...
3.
Rosado-Lugo J, Sun Y, Banerjee A, Cao Y, Datta P, Zhang Y, et al.
J Antibiot (Tokyo)
. 2022 May;
75(7):385-395.
PMID: 35618784
FtsZ inhibitors represent a new drug class as no drugs using this mode of action (MOA) have been approved by regulators. 3-alkoxy substituted 2,6-difluorobenzamide scaffold is one of the most...
4.
Yuan Y, Rosado-Lugo J, Zhang Y, Datta P, Sun Y, Cao Y, et al.
Antibiotics (Basel)
. 2022 Jan;
11(1).
PMID: 35052908
The ability to rescue the activity of antimicrobials that are no longer effective against bacterial pathogens such as is an attractive strategy to combat antimicrobial drug resistance. Herein, novel efflux...
5.
Jacobs J, Rosado-Lugo J, Cranz-Mileva S, Ciccaglione K, Tournier V, Zaratiegui M
Science
. 2015 Sep;
349(6255):1549-53.
PMID: 26404838
Long terminal repeat (LTR) retrotransposons are an abundant class of genomic parasites that replicate by insertion of new copies into the host genome. Fungal LTR retrotransposons prevent mutagenic insertions through...
6.
Rosado-Lugo J, Hampsey M
J Biol Chem
. 2014 Oct;
289(49):33916-26.
PMID: 25339178
Transitions between the different stages of the RNAPII transcription cycle involve the recruitment and exchange of factors, including mRNA capping enzymes, elongation factors, splicing factors, 3'-end-processing complexes, and termination factors....