Jesus A de la Fuente
Overview
Explore the profile of Jesus A de la Fuente including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
15
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0
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Recent Articles
1.
Cousido-Siah A, Ruiz F, Mitschler A, Porte S, de Lera A, Martin M, et al.
Acta Crystallogr D Biol Crystallogr
. 2014 Mar;
70(Pt 3):889-903.
PMID: 24598757
Aldo-keto reductases (AKRs) are mostly monomeric enzymes which fold into a highly conserved (α/β)8 barrel, while their substrate specificity and inhibitor selectivity are determined by interaction with residues located in...
2.
Vicent M, Manzanaro S, de la Fuente J, Duncan R
J Drug Target
. 2004 Dec;
12(8):503-15.
PMID: 15621676
1,5-diazaanthraquinones (DAQs) are promising anticancer drugs, however, their clinical potential is limited due to poor solubility. Conjugation of anticancer agents to hydrophilic water-soluble polymers can overcome this problem and has...
3.
Pipaon C, Gutierrez P, Carlos Montero J, Lorenzo M, Eguiraun A, de la Fuente J, et al.
Mol Cancer Ther
. 2002 Dec;
1(10):811-9.
PMID: 12492114
1,8-Diaza-anthracene-tetraones are novel intermediates in the synthesis of the antifolate antibiotic diazaquinomycin A that was found before to have potent antitumor activity. Three of them (CV65, CV66, and CV70) were...